Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Indian Journal of Surgical Oncology
Published in: Indian Journal of Surgical Oncology 3/2023

15-07-2023 | Sarcoma | Case Report

Case Report: Primary Ewing Sarcoma of the Penis

Authors: Soumen Das, Siddhartha Shankar Mishra, Kamalesh Rakshit, Rahul Agarwal

Published in: Indian Journal of Surgical Oncology | Issue 3/2023

Login to get access

Abstract

Background

Ewing sarcoma is a malignancy that commonly affects the skeletal system and primary extraskeletal involvement is rare. Extraskeletal Ewing sarcoma (EES) arises in soft tissue anywhere in the body. These are very rarely seen aggressive tumours. There have been only 7 reported cases of EES of penis.

Case Presentation

We report a 22-year-young patient who presented to our hospital with a ulcero-proliferative growth in the shaft of penis. There were no other complaints indicating any metastasis. Incisional biopsy was suggestive of invasive malignancy. He was scheduled for a partial penectomy. Final HPE and IHC were suggestive of EES.

Conclusion

EES as a subtype of Ewing sarcoma is rare and it can occur in any soft tissue site. Hence, clinicians need to differentiate this entity from other soft tissue sarcomas. Early diagnosis and timely treatment of EES are pivotal for a favourable prognosis due to its aggressive nature.
Appendix
Available only for authorised users
Literature
1.
Antonescu C (2014) Round cell sarcomas beyond Ewing: emerging entities. Histopathology 64(1):26–37CrossRefPubMed
2.
3.
Morrison BF (2014) Risk factors and prevalence of penile cancer. West Indian Med J 63(6):559–560PubMed
4.
Toh KL, Tan PH, Cheng WS (1999) Primary extraskeletal Ewing’s sarcoma of the external genitalia. J Urol 162(1):159–160CrossRefPubMed
5.
Yankelevich GR, Piraino J, Edwards D, Molligan J, Bernstein GT (2020) Noninvasive Ewing’s sarcoma of the penis: a rare entity. Urology 144:e15–e18CrossRefPubMed
6.
Weissferdt A, Kalhor N, Moran CA (2015) Ewing sarcoma with extensive neural differentiation: a clinicopathologic, immunohistochemical, and molecular analysis of three cases. Am J Clin Pathol 143(5):659–664CrossRefPubMed
7.
Ma Z, Brimo F, Zeizafoun N (2013) Primary Ewing’s sarcoma/primitive neuroectodermal tumor (ES/PNET) of the penis: a report of an extraordinarily unusual site and a literature review of extraskeletal Ewing’s sarcoma. Int J Surg Pathol 21(1):63–67CrossRefPubMed
8.
9.
Kilicaslan I, Karayigit E, Bulut F, Basaran M, Dizdar Y, Aslay I et al (2008) Ewing’s sarcoma/primitive neuroectodermal tumor (ES/PNET) of the penis. Int Urol Nephrol 40(1):113–115CrossRefPubMed
10.
Paruliya D, Sharma S, Gokhroo S, Yadav SS, Sharma KK, Sadasukhi TC. Primary neuroectodermal tumor of penis (PNET)--a case report. Urology 2007 70(4):811.e9–811.e10
11.
Fontaine C, Schots R, Braeckman J, Goossens A, Soete G, De Grève J. Long-term survival in an adult metastatic renal peripheral primitive neuroectodermal tumor (PPNET) with multimodality treatment including high-dose chemotherapy. Ann Oncol Off J Eur Soc Med Oncol. 1997 8(7):691–694
12.
Lee WS, Kim YH, Chee HK, Hwang JJ, Kim JS, Lee SA et al (2009) Multimodal treatment of primary extraskeletal Ewing’s sarcoma of the chest wall: report of 2 cases. Cancer Res Treat 41(2):108–112CrossRefPubMedPubMedCentral
13.
Sharma P, Bakshi H, Chheda Y, Beniwal S (2011) Primary Ewing’s sarcoma of penis – a rare case report. Indian J Surg Oncol 2(4):332–333CrossRefPubMed
Metadata
Title
Case Report: Primary Ewing Sarcoma of the Penis
Authors
Soumen Das
Siddhartha Shankar Mishra
Kamalesh Rakshit
Rahul Agarwal
Publication date
15-07-2023
Publisher
Springer India
Published in
Indian Journal of Surgical Oncology / Issue 3/2023
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-023-01793-x

Other articles of this Issue 3/2023

Indian Journal of Surgical Oncology 3/2023 Go to the issue

Case Report

Primary Gastric Synovial Sarcoma in a Young Male: a Rare Case Report and Review of Literature

Case Report

Soft Tissue and Lower Limb Muscle Metastases from Breast Carcinoma: An Unreported Entity

Original Article

Prognostic Value of IMP3 and Its Role as an Epithelial-Mesenchymal Transition Promoter in Breast Carcinoma

Desk of the Editor

Skill-Based Surgical Training: the Need of the Hour

Original Article

A Clinical and Immunopathological Analysis of Carcinoma of the Ovary with an Emphasis on Post-chemotherapy Histopathologic Changes

Original Article

Evaluation of Multiparametric Magnetic Resonance Imaging and Correlation with Radical Prostatectomy Histopathology Specimen in Prostate Cancer