Top

Neuroradiology

Published in:

01-09-2014 | Head and Neck Radiology

Salivary gland tumors of the parotid gland: CT and MR imaging findings with emphasis on intratumoral cystic components

Authors: Hiroki Kato, Masayuki Kanematsu, Haruo Watanabe, Keisuke Mizuta, Mitsuhiro Aoki

Published in: Neuroradiology | Issue 9/2014

Abstract

Introduction

The purpose of this study was to assess computed tomography (CT) and magnetic resonance (MR) imaging findings of salivary gland tumors of the parotid gland with emphasis on intratumoral cystic components.

Methods

Seventy-two histopathologically confirmed salivary gland tumors of the parotid gland (44 benign and 28 malignant), which underwent both CT and MR imaging including contrast-enhanced study, were included in this study. We retrospectively reviewed images for the presence, number, occupying rate, margin characteristics, distribution, and predominant MR signal intensity of intratumoral cystic components.

Results

The prevalence of cystic components was greater in malignant than benign tumors (79 vs. 50 %, p < 0.05). The number and occupying rate were similar between benign and malignant tumors. The irregular margins were more frequent in malignant than benign tumors (73 vs. 27 %, p < 0.01). The frequency of eccentric location was greater in benign than malignant tumors (91 vs. 55 %, p < 0.01), whereas the frequency of centric location was greater in malignant than benign tumors (32 vs. 0 %, p < 0.01). On T1-weighted images, the frequency of hyperintensity was greater in benign than malignant tumors (50 vs. 9 %, p < 0.01), whereas that of isointensity was greater in malignant than benign tumors (50 vs. 0 %, p < 0.01). Multiple logistic regression analysis showed that the absence of irregular margins of cystic components only was significantly correlated with the presence of benign salivary gland tumors (p < 0.01).

Conclusion

Imaging features of intratumoral cystic components may help to differentiate benign from malignant tumors of the parotid salivary gland.

Joe VQ, Westesson PL (1994) Tumors of the parotid gland: MR imaging characteristics of various histologic types. Am J Roentgenol 163(2):433–438CrossRef

Takashima S, Wang J, Takayama F, Momose M, Matsushita T, Kawakami S, Saito A, Ishiyama T (2001) Parotid masses: prediction of malignancy using magnetization transfer and MR imaging findings. Am J Roentgenol 176(6):1577–1584CrossRef

Christe A, Waldherr C, Hallett R, Zbaeren P, Thoeny H (2011) MR imaging of parotid tumors: typical lesion characteristics in mr imaging improve discrimination between benign and malignant disease. Am J Neuroradiol 32(7):1202–1207. doi:10.3174/Ajnr.A2520 PubMedCrossRef

Choi DS, Na DG, Byun HS, Ko YH, Kim CK, Cho JM, Lee HK (2000) Salivary gland tumors: evaluation with two-phase helical CT. Radiology 214(1):231–236. doi:10.1148/radiology.214.1.r00ja05231 PubMedCrossRef

Yabuuchi H, Fukuya T, Tajima T, Hachitanda Y, Tomita K, Koga M (2003) Salivary gland tumors: diagnostic value of gadolinium-enhanced dynamic MR imaging with histopathologic correlation. Radiology 226(2):345–354. doi:10.1148/radiol.2262011486 PubMedCrossRef

Matsushima N, Maeda M, Takamura M, Takeda K (2007) Apparent diffusion coefficients of benign and malignant salivary gland tumors. Comparison to histopathological findings. J Neuroradiol 34(3):183–189. doi:10.1016/j.neurad.2007.04.002 PubMedCrossRef

Habermann CR, Arndt C, Graessner J, Diestel L, Petersen KU, Reitmeier F, Ussmueller JO, Adam G, Jaehne M (2009) Diffusion-weighted echo-planar MR imaging of primary parotid gland tumors: is a prediction of different histologic subtypes possible? AJNR Am J Neuroradiol 30(3):591–596. doi:10.3174/ajnr.A1412 PubMedCrossRef

Kato H, Kanematsu M, Mizuta K, Aoki M (2013) Imaging findings of parapharyngeal space pleomorphic adenoma in comparison with parotid gland pleomorphic adenoma. Jpn J Radiol 31(11):724–730. doi:10.1007/s11604-013-0242-4 PubMedCrossRef

Minami M, Tanioka H, Oyama K, Itai Y, Eguchi M, Yoshikawa K, Murakami T, Sasaki Y (1993) Warthin tumor of the parotid gland: MR-pathologic correlation. AJNR Am J Neuroradiol 14(1):209–214PubMed

10.

Ikeda M, Motoori K, Hanazawa T, Nagai Y, Yamamoto S, Ueda T, Funatsu H, Ito H (2004) Warthin tumor of the parotid gland: diagnostic value of MR imaging with histopathologic correlation. AJNR Am J Neuroradiol 25(7):1256–1262PubMed

11.

Chawla AJ, Tan TY, Tan GJ (2006) Basal cell adenomas of the parotid gland: CT scan features. Eur J Radiol 58(2):260–265. doi:10.1016/j.ejrad.2005.12.001 PubMedCrossRef

12.

Okahara M, Kiyosue H, Matsumoto S, Hori Y, Tanoue S, Uchida D, Mori H, Kondo Y (2006) Basal cell adenoma of the parotid gland: MR imaging findings with pathologic correlation. AJNR Am J Neuroradiol 27(3):700–704PubMed

13.

Shi L, Wang YX, Yu C, Zhao F, Kuang PD, Shao GL (2012) CT and ultrasound features of basal cell adenoma of the parotid gland: a report of 22 cases with pathologic correlation. AJNR Am J Neuroradiol 33(3):434–438. doi:10.3174/ajnr.A2807 PubMedCrossRef

14.

Okahara M, Kiyosue H, Hori Y, Matsumoto A, Mori H, Yokoyama S (2003) Parotid tumors: MR imaging with pathological correlation. Eur Radiol 13:L25–L33. doi:10.1007/s00330-003-1999-0 PubMedCrossRef

15.

Suh SI, Seol HY, Kim TK, Lee NJ, Kim JH, Kim KA, Woo JS, Lee JH (2005) Acinic cell carcinoma of the head and neck: radiologic–pathologic correlation. J Comput Assist Tomogr 29(1):121–126PubMedCrossRef

16.

Kashiwagi N, Takashima S, Tomita Y, Araki Y, Yoshino K, Taniguchi S, Nakanishi K (2009) Salivary duct carcinoma of the parotid gland: clinical and MR features in six patients. Br J Radiol 82(982):800–804. doi:10.1259/bjr/29600237 PubMedCrossRef

17.

Bewick V, Cheek L, Ball J (2005) Statistics review 14: logistic regression. Crit Care 9(1):112–118. doi:10.1186/cc3045 PubMedCentralPubMedCrossRef

18.

Takeshita T, Tanaka H, Harasawa A, Kaminaga T, Imamura T, Furui S (2004) Benign pleomorphic adenoma with extensive cystic degeneration: unusual MR findings in two cases. Radiat Med 22(5):357–361PubMed

19.

Layfield LJ, Reznicek M, Lowe M, Bottles K (1992) Spontaneous infarction of a parotid gland pleomorphic adenoma. Report of a case with cytologic and radiographic overlap with a primary salivary gland malignancy. Acta Cytol 36(3):381–386PubMed

20.

Abiko Y, Kaku T, Shimono M, Noma H, Shigematsu T (1993) Large cyst formation in pleomorphic adenoma. Bull Tokyo Dent Coll 34(1):9–14PubMed

21.

Nagao K, Matsuzaki O, Saiga H, Sugano I, Shigematsu H, Kaneko T, Katoh T, Kitamura T (1982) Histopathologic studies of basal cell adenoma of the parotid gland. Cancer 50(4):736–745PubMedCrossRef

Title: Salivary gland tumors of the parotid gland: CT and MR imaging findings with emphasis on intratumoral cystic components
Authors: Hiroki Kato
Masayuki Kanematsu
Haruo Watanabe
Keisuke Mizuta
Mitsuhiro Aoki
Publication date: 01-09-2014
Publisher: Springer Berlin Heidelberg
Published in: Neuroradiology / Issue 9/2014
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-014-1386-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Salivary gland tumors of the parotid gland: CT and MR imaging findings with emphasis on intratumoral cystic components

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 9/2014

The recurrent artery of Heubner in routine selective cerebral angiography

European Society of Neuroradiology (ESNR)

FLAIR vascular hyperintensities and dynamic 4D angiograms for the estimation of collateral blood flow in posterior circulation occlusion

Woven Endobridge (WEB) Device for endovascular treatment of ruptured intracranial wide-neck aneurysms: a single-center experience

Differentiating intraparenchymal hemorrhage from contrast extravasation on post-procedural noncontrast CT scan in acute ischemic stroke patients undergoing endovascular treatment

Applicability of apparent diffusion coefficient ratios in preoperative diagnosis of common pediatric cerebellar tumors across two institutions