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Published in: Patient Safety in Surgery 1/2018

Open Access 01-12-2018 | Research

Safety of selective nonoperative management for blunt splenic trauma: the impact of concomitant injuries

Authors: Michel Paul Johan Teuben, Roy Spijkerman, Taco Johan Blokhuis, Roman Pfeifer, Henrik Teuber, Hans-Christoph Pape, Luke Petrus Hendrikus Leenen

Published in: Patient Safety in Surgery | Issue 1/2018

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Abstract

Background

Nonoperative management for blunt splenic injury is the preferred treatment. To improve the outcome of selective nonoperative therapy, the current challenge is to identify factors that predict failure. Little is known about the impact of concomitant injury on outcome. Our study has two goals. First, to determine whether concomitant injury affects the safety of selective nonoperative treatment. Secondly we aimed to identify factors that can predict failure.

Methods

From our prospective trauma registry we selected all nonoperatively treated adult patients with blunt splenic trauma admitted between 01.01.2000 and 12.21.2013. All concurrent injuries with an AIS ≥ 2 were scored. We grouped and compared patients sustaining solitary splenic injuries and patients with concomitant injuries. To identify specific factors that predict failure we used a multivariable regression analysis.

Results

A total of 79 patients were included. Failure of nonoperative therapy (n = 11) and complications only occurred in patients sustaining concomitant injury. Furthermore, ICU-stay as well as hospitalization time were significantly prolonged in the presence of associated injury (4 versus 13 days,p < 0.05). Mortality was not seen. Multivariable analysis revealed the presence of a femur fracture and higher age as predictors of failure.

Conclusions

Nonoperative management for hemodynamically normal patients with blunt splenic injury is feasible and safe, even in the presence of concurrent (non-hollow organ) injuries or a contrast blush on CT. However, associated injuries are related to prolonged intensive care unit- and hospital stay, complications, and failure of nonoperative management. Specifically, higher age and the presence of a femur fracture are predictors of failure.
Literature
1.
go back to reference Davis JJ, Cohn JRI, Nance FC. Diagnosis and management of blunt abdominal trauma. Ann Surg. 1976;183(6):672–8.CrossRef Davis JJ, Cohn JRI, Nance FC. Diagnosis and management of blunt abdominal trauma. Ann Surg. 1976;183(6):672–8.CrossRef
2.
go back to reference Cox EF. Blunt abdominal trauma. A 5-year analysis of 870 patients requiring celiotomy. Ann Surg. 1984;199(4):467–74.CrossRef Cox EF. Blunt abdominal trauma. A 5-year analysis of 870 patients requiring celiotomy. Ann Surg. 1984;199(4):467–74.CrossRef
3.
go back to reference King H, Shumacker HB Jr. Splenic studies. Suspectibility to infection after splenectomy performed in infancy. Ann Surg. 1952;136(2):239–42.CrossRef King H, Shumacker HB Jr. Splenic studies. Suspectibility to infection after splenectomy performed in infancy. Ann Surg. 1952;136(2):239–42.CrossRef
4.
go back to reference Pachter HL, Guth AA, Hofstetter SR, Spencer FC. Changing patterns in the management of splenic trauma: the impact of nonoperative management. Ann Surg. 1998;227(5):708–17.CrossRef Pachter HL, Guth AA, Hofstetter SR, Spencer FC. Changing patterns in the management of splenic trauma: the impact of nonoperative management. Ann Surg. 1998;227(5):708–17.CrossRef
5.
go back to reference Richardson JD. Changes in the management of injuries to the liver and spleen. J Am Coll Surg. 2005;200(5):648–69.CrossRef Richardson JD. Changes in the management of injuries to the liver and spleen. J Am Coll Surg. 2005;200(5):648–69.CrossRef
7.
go back to reference Rowell SE, Biffl WL, Brasel K, Moore EE, Albracht RA, et al. Western trauma association critical decisions in trauma: the management of adult blunt splenic trauma-2016 updates. J Trauma. 2017;82:787–93.CrossRef Rowell SE, Biffl WL, Brasel K, Moore EE, Albracht RA, et al. Western trauma association critical decisions in trauma: the management of adult blunt splenic trauma-2016 updates. J Trauma. 2017;82:787–93.CrossRef
8.
go back to reference Upadhyaya P, Simpson JS. Splenic trauma in children. Surg Gynecol Obstet. 1969;126(4):781–90. Upadhyaya P, Simpson JS. Splenic trauma in children. Surg Gynecol Obstet. 1969;126(4):781–90.
9.
go back to reference Dent D, Alsabrook G, Erickson BA, Meyers J, Wholey M, et al. Blunt splenic injuries: high nonoperative management rate can be achieved with selective embolization. J Trauma. 2004;56(5):1063–7.CrossRef Dent D, Alsabrook G, Erickson BA, Meyers J, Wholey M, et al. Blunt splenic injuries: high nonoperative management rate can be achieved with selective embolization. J Trauma. 2004;56(5):1063–7.CrossRef
10.
go back to reference Hunt JP, Lentz CW, Cairns BA, Ramadan FM, Smith DL, et al. Management and outcome of splenic injury: the results of a five-year statewide population-based study. Am Surg. 1996;62(11):911–7.PubMed Hunt JP, Lentz CW, Cairns BA, Ramadan FM, Smith DL, et al. Management and outcome of splenic injury: the results of a five-year statewide population-based study. Am Surg. 1996;62(11):911–7.PubMed
12.
go back to reference Harbrecht BG, Peitzman AB, Rivera L, Heil B, Croce M, et al. Contribution of age and gender to outcome of blunt splenic injury in adults: multicenter study of the eastern association for the surgery of trauma. J Trauma. 2001;51(5):887–95.CrossRef Harbrecht BG, Peitzman AB, Rivera L, Heil B, Croce M, et al. Contribution of age and gender to outcome of blunt splenic injury in adults: multicenter study of the eastern association for the surgery of trauma. J Trauma. 2001;51(5):887–95.CrossRef
13.
go back to reference Myers JG, Dent DL, Stewart RM, Gray GA, Smith DS, et al. Blunt splenic injuries: dedicated trauma surgeons can achieve a high rate of nonoperative success in patients of all ages. J Trauma. 2000;48(5):801–5.CrossRef Myers JG, Dent DL, Stewart RM, Gray GA, Smith DS, et al. Blunt splenic injuries: dedicated trauma surgeons can achieve a high rate of nonoperative success in patients of all ages. J Trauma. 2000;48(5):801–5.CrossRef
14.
go back to reference McIntyre LK, Schiff M, Jurkovich GJ. Failure of nonoperative management of splenic injuries: causes and consequences. Arch Surg. 2005;140(6):563–8.CrossRef McIntyre LK, Schiff M, Jurkovich GJ. Failure of nonoperative management of splenic injuries: causes and consequences. Arch Surg. 2005;140(6):563–8.CrossRef
15.
go back to reference Godley CD, Warren RL, Sheridan RL, McCabe CJ. Nonoperative management of blunt splenic injury in adults: age over 55 as a powerful indicator for failure. J Am Coll Surg. 1996;183(2):133–9.PubMed Godley CD, Warren RL, Sheridan RL, McCabe CJ. Nonoperative management of blunt splenic injury in adults: age over 55 as a powerful indicator for failure. J Am Coll Surg. 1996;183(2):133–9.PubMed
16.
go back to reference Cocanour CS, Moore FA, Ware DN, Marvin RG, Duke JH. Age should not be a consideration for nonoperative management of blunt splenic injury. J Trauma. 2000;58(4):606–10.CrossRef Cocanour CS, Moore FA, Ware DN, Marvin RG, Duke JH. Age should not be a consideration for nonoperative management of blunt splenic injury. J Trauma. 2000;58(4):606–10.CrossRef
17.
go back to reference Schurr MJ, Fabian TC, Gavant M, Croce MA, Kudsk KA, et al. Management of blunt splenic trauma: computed tomographic contrast blush predicts failure of nonoperative management. J Trauma. 1995;39(3):507–12.CrossRef Schurr MJ, Fabian TC, Gavant M, Croce MA, Kudsk KA, et al. Management of blunt splenic trauma: computed tomographic contrast blush predicts failure of nonoperative management. J Trauma. 1995;39(3):507–12.CrossRef
18.
go back to reference Omert LA, Salyer D, Dunham CM, Porter J, Silva A, et al. Implications of the “contrast blush” finding on computed tomogaphic scan of the spleen in trauma. J Trauma. 2000;51(2):272–7.CrossRef Omert LA, Salyer D, Dunham CM, Porter J, Silva A, et al. Implications of the “contrast blush” finding on computed tomogaphic scan of the spleen in trauma. J Trauma. 2000;51(2):272–7.CrossRef
19.
go back to reference Haan JM, Bochicchio GV, Kramer N, Scalea TM. Nonoperative management of blunt splenic injury: a 5-year experience. J Trauma. 2005;58(3):492–8.CrossRef Haan JM, Bochicchio GV, Kramer N, Scalea TM. Nonoperative management of blunt splenic injury: a 5-year experience. J Trauma. 2005;58(3):492–8.CrossRef
20.
go back to reference Velhamos GC, Toutouzas KG, Radin R, Chan L, Demetriades D. Nonoperative treatment of blunt injury to solid abdominal organs: a prospective study. Arch Surg. 2003;138(8):844–51.CrossRef Velhamos GC, Toutouzas KG, Radin R, Chan L, Demetriades D. Nonoperative treatment of blunt injury to solid abdominal organs: a prospective study. Arch Surg. 2003;138(8):844–51.CrossRef
21.
go back to reference Powell M, Courcoulas A, Gardner M, Lynch J, Harbrecht BG, et al. Management of blunt splenic trauma: significant differences between adults and children. Surgery. 1997;122(4):654–60.CrossRef Powell M, Courcoulas A, Gardner M, Lynch J, Harbrecht BG, et al. Management of blunt splenic trauma: significant differences between adults and children. Surgery. 1997;122(4):654–60.CrossRef
22.
go back to reference Malhotra AK, Latifi R, Fabian TC, Ivatury RR, Dhage S, et al. Multiplicity of solid organ injury: influence on management and outcomes after blunt abdominal trauma. J Trauma. 2003;54(4):925–9.CrossRef Malhotra AK, Latifi R, Fabian TC, Ivatury RR, Dhage S, et al. Multiplicity of solid organ injury: influence on management and outcomes after blunt abdominal trauma. J Trauma. 2003;54(4):925–9.CrossRef
23.
go back to reference Peitzman AB, Heil B, Rivera L, Federle MB, Harbrecht BG, et al. Blunt splenic injury in adults: multi-institutional study of the eastern Association for the Surgery of trauma. J Trauma. 2000;59(2):177–87.CrossRef Peitzman AB, Heil B, Rivera L, Federle MB, Harbrecht BG, et al. Blunt splenic injury in adults: multi-institutional study of the eastern Association for the Surgery of trauma. J Trauma. 2000;59(2):177–87.CrossRef
24.
go back to reference Yanar H, Ertekin C, Taviloglu K, Kabay B, Bakkaloglu H, et al. Nonoperative treatment of multiple intra-abdominal solid organ injury after blunt abdominal trauma. J Trauma. 2008;64(4):943–8.CrossRef Yanar H, Ertekin C, Taviloglu K, Kabay B, Bakkaloglu H, et al. Nonoperative treatment of multiple intra-abdominal solid organ injury after blunt abdominal trauma. J Trauma. 2008;64(4):943–8.CrossRef
25.
go back to reference Sartorelli KH, Frumiento C, Rogers FB, Osler TM. Nonoperative management of hepatic, splenic, and renal injuries in adults with multiple injuries. J Trauma. 2000;49(1):55–61.CrossRef Sartorelli KH, Frumiento C, Rogers FB, Osler TM. Nonoperative management of hepatic, splenic, and renal injuries in adults with multiple injuries. J Trauma. 2000;49(1):55–61.CrossRef
26.
go back to reference MacLeod JB, Lynn M, McKenney MG, Cohn SM, Murtha M. Early coagulopathy predicts mortality in trauma. J Trauma. 2003;55(1):39–44.CrossRef MacLeod JB, Lynn M, McKenney MG, Cohn SM, Murtha M. Early coagulopathy predicts mortality in trauma. J Trauma. 2003;55(1):39–44.CrossRef
27.
go back to reference Greenspan L, McLellan BA, Greig HRN. Abbreviated injury scale and injury severity score: a scoring chart. J Trauma. 1985;25(1):60–4.CrossRef Greenspan L, McLellan BA, Greig HRN. Abbreviated injury scale and injury severity score: a scoring chart. J Trauma. 1985;25(1):60–4.CrossRef
28.
go back to reference Cogbill TH, Moore EE, Jurkovich GJ, Mooris JA, Mucha P Jr, et al. Nonoperative mangemenent of blunt splenic trauma: a multicenter experience. J Trauma. 1989;29(10):1312–7.CrossRef Cogbill TH, Moore EE, Jurkovich GJ, Mooris JA, Mucha P Jr, et al. Nonoperative mangemenent of blunt splenic trauma: a multicenter experience. J Trauma. 1989;29(10):1312–7.CrossRef
29.
go back to reference Renzulli P, Gross T, Schnüringer B, Schoepfer AM, Inderbitzin D, et al. Management of blunt injuries to the spleen. Br J Surg. 2010;97:1696–703.CrossRef Renzulli P, Gross T, Schnüringer B, Schoepfer AM, Inderbitzin D, et al. Management of blunt injuries to the spleen. Br J Surg. 2010;97:1696–703.CrossRef
30.
go back to reference Ong AW, Eilertson KE, Reilly EF, Geng TA, Madbak F, et al. Nonoperativ management of splenic injuries: significance of age. J Surg Res. 2016;201:134.40.CrossRef Ong AW, Eilertson KE, Reilly EF, Geng TA, Madbak F, et al. Nonoperativ management of splenic injuries: significance of age. J Surg Res. 2016;201:134.40.CrossRef
31.
go back to reference Peitzman AB, Harbrecht BG, Rivera L, Heil B. EAST multiinstitutional trails workgroup. Failure of observation of blunt splenic injury in adults: variability in practice and adverse consequences. J Am Coll Surg. 2005;201(2):179–87.CrossRef Peitzman AB, Harbrecht BG, Rivera L, Heil B. EAST multiinstitutional trails workgroup. Failure of observation of blunt splenic injury in adults: variability in practice and adverse consequences. J Am Coll Surg. 2005;201(2):179–87.CrossRef
32.
go back to reference Rodrigues CJ, Sacchetti JC, Rodrigues AJ Jr. Age-related changes in the elastic fiber network of the human splenic capsule. Lymphology. 1999;31(2):64–9. Rodrigues CJ, Sacchetti JC, Rodrigues AJ Jr. Age-related changes in the elastic fiber network of the human splenic capsule. Lymphology. 1999;31(2):64–9.
33.
go back to reference Barone JE, Burns G, Svehlak SA, Tucker JB, Bell T, et al. Management of blunt splenic trauma in patients older than 55 years. Southern Connecticut regional trauma quality assurance committee. J Trauma. 1999;46(1):87–90.CrossRef Barone JE, Burns G, Svehlak SA, Tucker JB, Bell T, et al. Management of blunt splenic trauma in patients older than 55 years. Southern Connecticut regional trauma quality assurance committee. J Trauma. 1999;46(1):87–90.CrossRef
34.
go back to reference Miller PR, Croce MA, Bee TK, Malhotra AK, Fabian TC. Associated injuries in blunt solid organ trauma: implications for missed injury in nonoperative management. J Trauma. 2002;53(2):238–42.CrossRef Miller PR, Croce MA, Bee TK, Malhotra AK, Fabian TC. Associated injuries in blunt solid organ trauma: implications for missed injury in nonoperative management. J Trauma. 2002;53(2):238–42.CrossRef
35.
go back to reference Kemmeter PR, Hoedema RE, Foote JA, Scholten DJ. Concomitant blunt enteric injuries with injuries of the liver and spleen: a dilemma for trauma surgeons. Am Surg. 2001;67(3):221–5.PubMed Kemmeter PR, Hoedema RE, Foote JA, Scholten DJ. Concomitant blunt enteric injuries with injuries of the liver and spleen: a dilemma for trauma surgeons. Am Surg. 2001;67(3):221–5.PubMed
36.
go back to reference Watts DD, Fakhry SM. EAST multi-institutional hollow viscus injury research group. Incidence of hollow viscus injury in blunt trauma: an analysis from 275,557 trauma admissions from the East multi-institutional trial. J Trauma. 2003;54(2):289–94.CrossRef Watts DD, Fakhry SM. EAST multi-institutional hollow viscus injury research group. Incidence of hollow viscus injury in blunt trauma: an analysis from 275,557 trauma admissions from the East multi-institutional trial. J Trauma. 2003;54(2):289–94.CrossRef
37.
go back to reference Nance ML, Peden GW, Shapiro MB, Kauder DR, Rotondo MF, et al. Solid viscus injury predics major hollow viscus injury in blunt abdominal trauma. J Trauma. 1997;43(4):618–22.CrossRef Nance ML, Peden GW, Shapiro MB, Kauder DR, Rotondo MF, et al. Solid viscus injury predics major hollow viscus injury in blunt abdominal trauma. J Trauma. 1997;43(4):618–22.CrossRef
38.
go back to reference Brugere C, Arvieux C, Dubuisson V, Dubuisson V, Guillon F, et al. Early embolization in the nonoperative management of blunt splenic injuries: a retrospective multicenter study. J Chir (Paris). 2008;145(2):126–32.CrossRef Brugere C, Arvieux C, Dubuisson V, Dubuisson V, Guillon F, et al. Early embolization in the nonoperative management of blunt splenic injuries: a retrospective multicenter study. J Chir (Paris). 2008;145(2):126–32.CrossRef
39.
go back to reference Olthof DC, Joose P, Bossuyt PM, de Rooij PP, Leenen LP, et al. Observation versus embolization in patients with blunt splenic injury after trauma: a prospensity score analysis. World J Surg. 2016;40(5):126–71.CrossRef Olthof DC, Joose P, Bossuyt PM, de Rooij PP, Leenen LP, et al. Observation versus embolization in patients with blunt splenic injury after trauma: a prospensity score analysis. World J Surg. 2016;40(5):126–71.CrossRef
Metadata
Title
Safety of selective nonoperative management for blunt splenic trauma: the impact of concomitant injuries
Authors
Michel Paul Johan Teuben
Roy Spijkerman
Taco Johan Blokhuis
Roman Pfeifer
Henrik Teuber
Hans-Christoph Pape
Luke Petrus Hendrikus Leenen
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Patient Safety in Surgery / Issue 1/2018
Electronic ISSN: 1754-9493
DOI
https://doi.org/10.1186/s13037-018-0179-8

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