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Published in: Surgical Endoscopy 7/2014

01-07-2014

Safety of elective laparoscopic cholecystectomy in patients on dialysis: an analysis of the ACS NSQIP database

Authors: A. Rao, A. Polanco, E. Chin, C. M. Divino, S. Qiu, S. Q. Nguyen

Published in: Surgical Endoscopy | Issue 7/2014

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Abstract

Background

Laparoscopic cholecystectomy (LC) remains one of the most frequently performed surgical procedures. The safety of LC in patients with renal disease is unclear. The postoperative outcomes of elective LC in patients on dialysis were studied and risk factors associated with longer length of stay and mortality were sought.

Methods

Patients who underwent LC between the dates of 1 January 2007 and 31 December 2010 at all hospitals in North America participating in the American College of Surgeons National Surgical Quality Improvement Project were reviewed. Data from 80,995 patients were collected, and the patients on dialysis (N = 512) were separated and compared with those of patients not on dialysis (N = 80,483).

Results

Postoperative complications for patients on and not on dialysis, respectively, included mortality (4.1 vs. 0.2 %, p < 0.001), myocardial infarction (0.8 vs. 0.1 %, p = 0.002), pneumonia (2.3 vs. 0.4 %, p < 0.001), sepsis (3.1 vs. 0.4 %, p < 0.001), and return to operating room (4.3 vs. 1.0 %, p < 0.001). In patients on dialysis, multivariate analysis was used to identify risk factors, including congestive heart failure and prior cardiac surgery as significant independent predictors of longer length of stay and mortality.

Conclusion

Patients on dialysis who undergo LC should be carefully selected due to the significantly higher complication and mortality rate. Several predictors of longer length of stay and mortality were identified that can determine which patients on dialysis are good candidates for LC.
Literature
1.
go back to reference Deziel DJ, Millikan KW, Economou SG et al (1993) Complications of cholecystectomy: a national survey of 4,292 hospitals and an analysis of 77,604 cases. Am J Surg 165:9–14PubMedCrossRef Deziel DJ, Millikan KW, Economou SG et al (1993) Complications of cholecystectomy: a national survey of 4,292 hospitals and an analysis of 77,604 cases. Am J Surg 165:9–14PubMedCrossRef
2.
go back to reference Shea JA, Healey MJ, Berlin JA et al (1996) Mortality and complications associated with laparoscopic cholecystectomy. A meta-analysis. Ann Surg 224:609–620PubMedCentralPubMedCrossRef Shea JA, Healey MJ, Berlin JA et al (1996) Mortality and complications associated with laparoscopic cholecystectomy. A meta-analysis. Ann Surg 224:609–620PubMedCentralPubMedCrossRef
4.
go back to reference Bingener J, Richards ML, Schwesinger WH et al (2003) Laparoscopic cholecystectomy for elderly patients: gold standard for golden years? Arch Surg 138:535–536CrossRef Bingener J, Richards ML, Schwesinger WH et al (2003) Laparoscopic cholecystectomy for elderly patients: gold standard for golden years? Arch Surg 138:535–536CrossRef
5.
go back to reference Puggioni A, Wong LL (2003) A metaanalysis of laparoscopic cholecystectomy in patients with cirrhosis. J Am Coll Surg 197:921–926PubMedCrossRef Puggioni A, Wong LL (2003) A metaanalysis of laparoscopic cholecystectomy in patients with cirrhosis. J Am Coll Surg 197:921–926PubMedCrossRef
6.
go back to reference Fleisher LA, Pasternak LR, Herbert R, Anderson GF (2004) Inpatient hospital admission and death after outpatient surgery in elderly patients: importance of patient and system characteristics and location of care. Arch Surg 139:67–72PubMedCrossRef Fleisher LA, Pasternak LR, Herbert R, Anderson GF (2004) Inpatient hospital admission and death after outpatient surgery in elderly patients: importance of patient and system characteristics and location of care. Arch Surg 139:67–72PubMedCrossRef
7.
go back to reference Khuri SF, Daley J, Henderson W et al (1995) The National Veterans Administration Surgical Risk Study: risk adjustment for the comparative assessment of the quality of surgicalcare. J Am Coll Surg 180:519–531PubMed Khuri SF, Daley J, Henderson W et al (1995) The National Veterans Administration Surgical Risk Study: risk adjustment for the comparative assessment of the quality of surgicalcare. J Am Coll Surg 180:519–531PubMed
8.
go back to reference Khuri SF, Daley J, Henderson W et al (1998) The Department of Veterans Affairs’ NSQIP: the first national, validated, outcome-based, risk-adjusted, and peer-controlled program for the measurement and enhancement of the quality of surgical care. National VA Surgical Quality ImprovementProgram. Ann Surg 228:491–507PubMedCentralPubMedCrossRef Khuri SF, Daley J, Henderson W et al (1998) The Department of Veterans Affairs’ NSQIP: the first national, validated, outcome-based, risk-adjusted, and peer-controlled program for the measurement and enhancement of the quality of surgical care. National VA Surgical Quality ImprovementProgram. Ann Surg 228:491–507PubMedCentralPubMedCrossRef
10.
go back to reference Khuri SF, Henderson WG, Daley J et al (2007) The patient safety in surgery study: background, study design, and patient populations. J Am Coll Surg 204:1089–1102PubMedCrossRef Khuri SF, Henderson WG, Daley J et al (2007) The patient safety in surgery study: background, study design, and patient populations. J Am Coll Surg 204:1089–1102PubMedCrossRef
11.
go back to reference Yeh CN, Chen MF, Jan YY (2005) Laparoscopic cholecystectomy for 58 end stage renal disease patients. Surg Endosc 19:915–918PubMedCrossRef Yeh CN, Chen MF, Jan YY (2005) Laparoscopic cholecystectomy for 58 end stage renal disease patients. Surg Endosc 19:915–918PubMedCrossRef
12.
go back to reference Ekici Y, Karakayali F, Yagmurdur MC et al (2009) Laparoscopic cholecystectomy in patients undergoing continuous ambulatory peritoneal dialysis: a case-control study. Surg Laparosc Endosc Percutan Tech 19:101–105PubMedCrossRef Ekici Y, Karakayali F, Yagmurdur MC et al (2009) Laparoscopic cholecystectomy in patients undergoing continuous ambulatory peritoneal dialysis: a case-control study. Surg Laparosc Endosc Percutan Tech 19:101–105PubMedCrossRef
13.
go back to reference Brenowitz JB, Williams CD, Edwards WS (1977) Major surgery in patients with chronic renal failure. Am J Surg 134:765–769PubMedCrossRef Brenowitz JB, Williams CD, Edwards WS (1977) Major surgery in patients with chronic renal failure. Am J Surg 134:765–769PubMedCrossRef
14.
go back to reference Lale AM, Wheatley TJ, Nicholson ML (1966) Laparoscopic cholecystectomy in a patient receiving continuous ambulatory peritoneal dialysis. Br J Surg 83:1543CrossRef Lale AM, Wheatley TJ, Nicholson ML (1966) Laparoscopic cholecystectomy in a patient receiving continuous ambulatory peritoneal dialysis. Br J Surg 83:1543CrossRef
15.
go back to reference Schneider CR, Cobb W, Patel S et al (2009) Elective surgery in patients with end stage renal disease: what’s the risk? Am Surg 75:790–793PubMed Schneider CR, Cobb W, Patel S et al (2009) Elective surgery in patients with end stage renal disease: what’s the risk? Am Surg 75:790–793PubMed
16.
go back to reference Bamgbade OA, Rutter TW, NAfiu OO, Dorje P (2007) Postoperative complications in obese and nonobese patients. World J Surg 31:556–560PubMedCrossRef Bamgbade OA, Rutter TW, NAfiu OO, Dorje P (2007) Postoperative complications in obese and nonobese patients. World J Surg 31:556–560PubMedCrossRef
17.
go back to reference Birkmeyer JD, Hamby LS, Birkmeyer CM et al (2001) Is unplanned return to the operating room a useful quality indicator in general surgery? Arch Surg 136:405–411PubMedCrossRef Birkmeyer JD, Hamby LS, Birkmeyer CM et al (2001) Is unplanned return to the operating room a useful quality indicator in general surgery? Arch Surg 136:405–411PubMedCrossRef
18.
go back to reference Virkkunen J, Heikkinen M, Lepantalo M et al (2004) Diabetes as an independent risk factor for early postoperative complications in critical limb ischemia. J Vasc Surg 40:761–767PubMedCrossRef Virkkunen J, Heikkinen M, Lepantalo M et al (2004) Diabetes as an independent risk factor for early postoperative complications in critical limb ischemia. J Vasc Surg 40:761–767PubMedCrossRef
19.
go back to reference Go AS, Chertow GM, Fan D et al (2004) Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351:1296–1305PubMedCrossRef Go AS, Chertow GM, Fan D et al (2004) Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351:1296–1305PubMedCrossRef
20.
go back to reference Livingston EH, Rege RV (2004) A nationwide study of conversion from laparoscopic to open cholecystectomy. Am J Surg 188:205–211PubMedCrossRef Livingston EH, Rege RV (2004) A nationwide study of conversion from laparoscopic to open cholecystectomy. Am J Surg 188:205–211PubMedCrossRef
21.
go back to reference Moffat FL, Deitel M, Thompson DA (1982) Abdominal surgery in patients undergoing long-term peritoneal dialysis. Surgery 92:598–604PubMed Moffat FL, Deitel M, Thompson DA (1982) Abdominal surgery in patients undergoing long-term peritoneal dialysis. Surgery 92:598–604PubMed
22.
go back to reference Jaar BG, Coresh J, Plantinga LC et al (2005) Comparing the risk for death with peritoneal dialysis and hemodialysis in a national cohort of patients with chronic kidney disease. Ann Intern Med 143:174–183PubMedCrossRef Jaar BG, Coresh J, Plantinga LC et al (2005) Comparing the risk for death with peritoneal dialysis and hemodialysis in a national cohort of patients with chronic kidney disease. Ann Intern Med 143:174–183PubMedCrossRef
Metadata
Title
Safety of elective laparoscopic cholecystectomy in patients on dialysis: an analysis of the ACS NSQIP database
Authors
A. Rao
A. Polanco
E. Chin
C. M. Divino
S. Qiu
S. Q. Nguyen
Publication date
01-07-2014
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 7/2014
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-014-3454-5

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