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CardioVascular and Interventional Radiology

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01-03-2018 | Clinical Investigation

Safety Considerations and Local Tumor Control Following Percutaneous Image-Guided Cryoablation of T1b Renal Tumors

Authors: Sonia Hebbadj, Roberto Luigi Cazzato, Julien Garnon, Benham Shaygi, Xavier Buy, Georgia Tsoumakidou, Herve Lang, Afshin Gangi

Published in: CardioVascular and Interventional Radiology | Issue 3/2018

Abstract

Objective

To retrospectively assess the safety and oncological efficacy of percutaneous image-guided cryoablation (CA) of T1b (> 4 cm/< 7 cm) renal tumors.

Materials and Methods

Institutional electronic records were retrospectively reviewed to identify the patients who had undergone percutaneous CA of T1b renal tumors between 2008 and 2016. CA was proposed by a multidisciplinary tumor board for cases with poor renal function or a single kidney; unsuitable for surgical resection; or genetic syndromes predisposing to multiple hereditary renal tumors.

Patients’ demographics, procedural and follow-up data were accurately collected and analyzed.

Results

Twenty-seven consecutive patients (12 females, 15 males; mean age 72.3 ± 14.3 years) were included. Mean tumor diameter was 47.9 ± 6.3 mm. MRI guidance was used in 6/27 cases (22.2%) and CT guidance in the remaining 21/27 (77.8%) cases. Hydro- and/or carbo-dissections were necessary in 21/27 cases (77.8%). Complications graded ≥ II were reported in three (11.1%) patients. Technical success and technical efficacy were 100 and 87.5%, respectively. Local tumor control (LTC) evaluated at imaging follow-up ≥ 6 months was 82.6, 72.3 and 60.3% at 12-, 24- and 36-month follow-up, respectively. One patient passed away 3 months after CA due to the metastatic evolution of the primary kidney cancer.

Conclusion

Percutaneous CA of T1b renal tumors is safe and satisfactory rates of LTC are expected at the early follow-ups. Further studies are needed to confirm the long-term efficacy of this procedure.

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Title: Safety Considerations and Local Tumor Control Following Percutaneous Image-Guided Cryoablation of T1b Renal Tumors
Authors: Sonia Hebbadj
Roberto Luigi Cazzato
Julien Garnon
Benham Shaygi
Xavier Buy
Georgia Tsoumakidou
Herve Lang
Afshin Gangi
Publication date: 01-03-2018
Publisher: Springer US
Published in: CardioVascular and Interventional Radiology / Issue 3/2018
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-017-1820-0

At a glance: The STEP trials

Springer Medicine

Safety Considerations and Local Tumor Control Following Percutaneous Image-Guided Cryoablation of T1b Renal Tumors

Abstract

Objective

Materials and Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Materials and Methods

Results

Conclusion

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