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Open Access 01-02-2011 | Poster presentation

Safety and tolerability of an ovine-derived polyclonal anti-TNFα Fab fragment (AZD9773) in patients with severe sepsis

Authors: P Morris, B Zeno, A Bernard, X Huang, S Simonson, G Bernard

Published in: Critical Care | Special Issue 1/2011

Excerpt

Sepsis remains a significant medical problem. TNFα is a central cytokine in sepsis pathophysiology. We conducted a phase IIa trial in patients with severe sepsis to assess the safety and tolerability of an intravenously infused ovine-derived polyclonal anti-TNFα Fab fragment (AZD9773). …

Title: Safety and tolerability of an ovine-derived polyclonal anti-TNFα Fab fragment (AZD9773) in patients with severe sepsis
Authors: P Morris
B Zeno
A Bernard
X Huang
S Simonson
G Bernard
Publication date: 01-02-2011
Publisher: BioMed Central
Published in: Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc9683

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Safety and tolerability of an ovine-derived polyclonal anti-TNFα Fab fragment (AZD9773) in patients with severe sepsis

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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