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01-02-2015 | Original Article

Role of surgery in multi-modality treatment for carcinomatous pleuritis in patients with non-small cell lung cancer

Authors: Tetsuhiko Go, Noriyuki Misaki, Natsumi Matsuura, Sung Soo Chang, Shintarou Tarumi, Hiroyasu Yokomise

Published in: Surgery Today | Issue 2/2015

Abstract

Objective

To evaluate the role of surgery in the treatment of the patients with non-small cell lung cancer with pleural dissemination.

Methods

The clinical records of 25 patients (mean age 69 years) diagnosed with carcinomatous pleuritis during a thoracotomy by pathological examination and followed by surgery between 1994 and 2012 were reviewed. The treatment modality, including surgery, the clinicopathologic characteristics and 5-year survival were analyzed.

Results

There were 16 adenocarcinomas, 6 squamous cell carcinomas and 3 large cell carcinomas. Surgery included resection of the main tumor by partial resection in 10 cases, segmentectomy in 2 cases, lobar resection in 12 cases and bilobectomy in 1 case. Intrathoracic irrigation was performed in 20 cases. The pathological N status was N0/N1/N2/Nx: 10/6/7/2. Fifteen patients received adjuvant therapy. The overall 5-year survival rate was 22.2 %. The 5-year survival rates of the N0, N1 and N2 groups were 36.0, 16.7 and 14.3 %, respectively (p = 0.0068). Nine patients lived more than 3 years including 5 in N0, 3 in N1 and 1 in N2.

Conclusions

Surgery should not be excluded from the multi-modality treatment of patients with carcinomatous pleuritis because there are some patients who could benefit from surgery especially if they are in N0 status.

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Title: Role of surgery in multi-modality treatment for carcinomatous pleuritis in patients with non-small cell lung cancer
Authors: Tetsuhiko Go
Noriyuki Misaki
Natsumi Matsuura
Sung Soo Chang
Shintarou Tarumi
Hiroyasu Yokomise
Publication date: 01-02-2015
Publisher: Springer Japan
Published in: Surgery Today / Issue 2/2015
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-014-0987-0

At a glance: The STEP trials

Springer Medicine

Role of surgery in multi-modality treatment for carcinomatous pleuritis in patients with non-small cell lung cancer

Abstract

Objective

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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