Top

Published in:

01-12-2015 | REVIEW ARTICLE

Role of Positron Emission Tomography-Computed Tomography in Locally Advanced Breast Cancer

Authors: Pankaj Kumar Garg, Suryanarayana V. S. Deo, Rakesh Kumar

Published in: Indian Journal of Surgical Oncology | Issue 4/2015

Abstract

Breast cancer is the commonest cancer among women and leading cause of cancer related mortality worldwide. Locally advanced breast cancer is the common subgroup of breast cancer encountered in developing countries. The last decade witnessed the voluminous upsurge in the use of positron emission tomography-computed tomography. Its role has been evaluated in different aspects of breast cancer - diagnosing and staging the disease, assessing the therapeutic response to chemotherapy, and restaging the recurrent disease. The present review aims to delineate the current role of positron emission tomography-computed tomography in the management of locally advanced breast cancer, based on available literature.

Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M et al (2015) Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136:E359–86CrossRefPubMed

Cancer Staging [Internet]. National Cancer Institute. [cited 2015 Apr 12]. Available from: http://www.cancer.gov/cancertopics/diagnosis-staging/staging/staging-fact-sheet

Smith JA, Andreopoulou E (2004) An overview of the status of imaging screening technology for breast cancer. Ann Oncol 15:i18–26CrossRefPubMed

Manohar K, Mittal BR, Bhoil A, Bhattacharya A, Singh G (2013) Role of 18 F-FDG PET/CT in identifying distant metastatic disease missed by conventional imaging in patients with locally advanced breast cancer. Nucl Med Commun 34:557–61CrossRefPubMed

Garg PK (2014) Preoperative fluorodeoxyglucose positron emission tomography-computed tomography in papillary thyroid cancer: a futile exercise. J Int Med Res 42:243–4CrossRefPubMed

Challa VR, Srivastava A, Dhar A, Parshad R, Bal C, Mohan Reddy Gona R et al (2013) Role of fluorine-18-labeled 2-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography in the evaluation of axillary lymph node involvement in operable breast cancer in comparison with sentinel lymph node biopsy. Indian J Nucl Med 28:138–43CrossRefPubMedPubMedCentral

Deo SVS, Varma MC, Shukla NK (2008) Management of patients with breast cancer: are we ready in India for sentinel lymph node biopsy? Natl Med J India 21:27–30PubMed

Groheux D, Hindié E, Rubello D, Espié M, Baillet G, Giacchetti S et al (2009) Should FDG PET/CT be used for the initial staging of breast cancer? Eur J Nucl Med Mol Imaging 36:1539–42CrossRefPubMed

Heusner TA, Kuemmel S, Umutlu L, Koeninger A, Freudenberg LS, Hauth EAM et al (2008) Breast cancer staging in a single session: whole-body PET/CT mammography. J Nucl Med 49:1215–22CrossRefPubMed

10.

Choi YJ, Shin YD, Kang YH, Lee MS, Lee MK, Cho BS et al (2012) The effects of preoperative (18)F-FDG PET/CT in breast cancer patients in comparison to the conventional imaging study. J Breast Cancer 15:441–8CrossRefPubMedPubMedCentral

11.

Jung NY, Kim SH, Kim SH, Seo YY, Oh JK, Choi HS et al (2015) Effectiveness of breast MRI and 18 F-FDG PET/CT for the preoperative staging of invasive lobular carcinoma versus ductal carcinoma. J Breast Cancer 18:63–72CrossRefPubMedPubMedCentral

12.

Baruah BP, Goyal A, Young P, Douglas-Jones AG, Mansel RE (2010) Axillary node staging by ultrasonography and fine-needle aspiration cytology in patients with breast cancer. Br J Surg 97:680–3CrossRefPubMed

13.

Sianesi M, Ceci G, Ghirarduzzi A, Del Rio P, Guazzi A, Pisanelli B et al (2009) Use of axillary ultrasonography in breast cancer: a useful tool to reduce sentinel node procedures. Ann Ital Chir 80:315–8PubMed

14.

Van Rijk MC, Deurloo EE, Nieweg OE, Gilhuijs KGA, Peterse JL, Rutgers EJT et al (2006) Ultrasonography and fine-needle aspiration cytology can spare breast cancer patients unnecessary sentinel lymph node biopsy. Ann Surg Oncol 13:31–5CrossRefPubMed

15.

Leenders MWH, Broeders M, Croese C, Richir MC, Go HLS, Langenhorst BLM et al (2012) Ultrasound and fine needle aspiration cytology of axillary lymph nodes in breast cancer. To do or not to do? Breast Edinb Scotl 21:578–83CrossRef

16.

Pritchard KI, Julian JA, Holloway CMB, McCready D, Gulenchyn KY, George R et al (2012) Prospective study of 2-[¹⁸ F]fluorodeoxyglucose positron emission tomography in the assessment of regional nodal spread of disease in patients with breast cancer: an Ontario clinical oncology group study. J Clin Oncol 30:1274–9CrossRefPubMed

17.

Cooper KL, Harnan S, Meng Y, Ward SE, Fitzgerald P, Papaioannou D et al (2011) Positron emission tomography (PET) for assessment of axillary lymph node status in early breast cancer: a systematic review and meta-analysis. Eur J Surg Oncol 37:187–98CrossRefPubMed

18.

Robertson IJ, Hand F, Kell MR (2011) FDG-PET/CT in the staging of local/regional metastases in breast cancer. Breast Edinb Scotl 20:491–4CrossRef

19.

Groheux D, Giacchetti S, Delord M, Hindié E, Vercellino L, Cuvier C et al (2013) 18 F-FDG PET/CT in staging patients with locally advanced or inflammatory breast cancer: comparison to conventional staging. J Nucl Med 54:5–11CrossRefPubMed

20.

Fuster D, Duch J, Paredes P, Velasco M, Muñoz M, Santamaría G et al (2008) Preoperative staging of large primary breast cancer with [18 F]fluorodeoxyglucose positron emission tomography/computed tomography compared with conventional imaging procedures. J Clin Oncol 26:4746–51CrossRefPubMed

21.

Mahner S, Schirrmacher S, Brenner W, Jenicke L, Habermann CR, Avril N et al (2008) Comparison between positron emission tomography using 2-[fluorine-18]fluoro-2-deoxy-D-glucose, conventional imaging and computed tomography for staging of breast cancer. Ann Oncol 19:1249–54CrossRefPubMed

22.

Niikura N, Costelloe CM, Madewell JE, Hayashi N, Yu T-K, Liu J et al (2011) FDG-PET/CT compared with conventional imaging in the detection of distant metastases of primary breast cancer. Oncologist 16:1111–9CrossRefPubMedPubMedCentral

23.

NCCN clinical practice guidelines in oncology (NCCN guidelines®) Breast Cancer, Version 2.2015 [Internet]. [cited 2015 May 10]. Available from: http://www.nccn.org/professionals/physician_gls/pdf/breast.pdf

24.

Rosen EL, Eubank WB, Mankoff DA (2007) FDG PET, PET/CT, and breast cancer imaging. RadioGraphics 27:S215–29CrossRefPubMed

25.

Morris PG, Lynch C, Feeney JN, Patil S, Howard J, Larson SM et al (2010) Integrated positron emission tomography/computed tomography may render bone scintigraphy unnecessary to investigate suspected metastatic breast cancer. J Clin Oncol 28:3154–9CrossRefPubMedPubMedCentral

26.

Van der Hoeven JJM, Krak NC, Hoekstra OS, Comans EFI, Boom RPA, van Geldere D et al (2004) 18 F-2-fluoro-2-deoxy-d-glucose positron emission tomography in staging of locally advanced breast cancer. J Clin Oncol 22:1253–9CrossRefPubMed

27.

Deo SVS, Bhutani M, Shukla NK, Raina V, Rath GK, Purkayasth J (2003) Randomized trial comparing neo-adjuvant versus adjuvant chemotherapy in operable locally advanced breast cancer (T4b N0-2 M0). J Surg Oncol 84:192–7CrossRefPubMed

28.

Ozkan E (2013) Positron emission tomography/computed tomography in locally advanced breast cancer. Exp Oncol 35:253–7PubMed

29.

Rousseau C, Devillers A, Sagan C, Ferrer L, Bridji B, Campion L et al (2006) Monitoring of early response to neoadjuvant chemotherapy in stage II and III breast cancer by [18 F]fluorodeoxyglucose positron emission tomography. J Clin Oncol 24:5366–72CrossRefPubMed

30.

Kumar A, Kumar R, Seenu V, Gupta SD, Chawla M, Malhotra A et al (2009) The role of 18 F-FDG PET/CT in evaluation of early response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. Eur Radiol 19:1347–57CrossRefPubMed

Title: Role of Positron Emission Tomography-Computed Tomography in Locally Advanced Breast Cancer
Authors: Pankaj Kumar Garg
Suryanarayana V. S. Deo
Rakesh Kumar
Publication date: 01-12-2015
Publisher: Springer India
Published in: Indian Journal of Surgical Oncology / Issue 4/2015
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI: https://doi.org/10.1007/s13193-015-0437-5

At a glance: The STEP trials

Springer Medicine

Role of Positron Emission Tomography-Computed Tomography in Locally Advanced Breast Cancer

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 4/2015

Granular Cell Tumor of Breast: a Case Report and Review of Literature

Time Trends in Breast Cancer Among Indian Women Population: An Analysis of Population Based Cancer Registry Data

Pattern of External Breast Prosthesis Use by Post Mastectomy Breast Cancer Patients in India: Descriptive Study from Tertiary Care Centre

Integrative Oncology—Finding an Indian Solution to Universal Problems for Holistic Cancer Care!!

Malignant Peripheral Nerve Sheath Tumour of the Male Breast with Nodal Metastasis

Options for Breast Reconstruction after Mastectomy for Carcinoma of the Breast: An Observational Experience at MSKCC, New York under UICC Fellowship