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01-09-2016 | Original Article

Role of local ablative techniques (Radiofrequency ablation and Irreversible Electroporation) in the treatment of pancreatic cancer

Authors: Salvatore Paiella, Roberto Salvia, Roberto Girelli, Isabella Frigerio, Alessandro Giardino, Mirko D’Onofrio, Giulia De Marchi, Claudio Bassi

Published in: Updates in Surgery | Issue 3/2016

Abstract

Thanks to continuous research and investment in technology, the ablation of tumors has become common. Through the application of different types of energy is possible to induce cellular injury of the neoplastic tissue, leading to cellular death. Radiofrequency ablation (RFA) and irreversible electroporation (IRE) represent the most applied ablative techniques on pancreatic cancer. RFA and IRE, causing necrosis and apoptosis of neoplastic cells, are able to destroy neoplastic tissue, to drastically modify the neoplastic microenvironment and, possibly, to stimulate both directly and indirectly the anti-tumor immune system. This article provides part of our experience with the application of RFA and IRE on pancreatic adenocarcinoma (PDAC).

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Title: Role of local ablative techniques (Radiofrequency ablation and Irreversible Electroporation) in the treatment of pancreatic cancer
Authors: Salvatore Paiella
Roberto Salvia
Roberto Girelli
Isabella Frigerio
Alessandro Giardino
Mirko D’Onofrio
Giulia De Marchi
Claudio Bassi
Publication date: 01-09-2016
Publisher: Springer Milan
Published in: Updates in Surgery / Issue 3/2016
Print ISSN: 2038-131X
Electronic ISSN: 2038-3312
DOI: https://doi.org/10.1007/s13304-016-0385-9

At a glance: The STEP trials

Springer Medicine

Role of local ablative techniques (Radiofrequency ablation and Irreversible Electroporation) in the treatment of pancreatic cancer

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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