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European Journal of Nuclear Medicine and Molecular Imaging

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Open Access 01-01-2019 | Short Communication

Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation

Authors: Philippa Meershoek, Matthias N. van Oosterom, Hervé Simon, Laurent Mengus, Tobias Maurer, Pim J. van Leeuwen, Esther M. K. Wit, Henk G. van der Poel, Fijs W. B. van Leeuwen

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 1/2019

Abstract

Purpose

Radioguided surgery has been widely used for clinical procedures such as sentinel node resections. In the (robot-assisted) laparoscopic setting radioguidance is realized using laparoscopic gamma probes, which have limited maneuverability. To increase the rotational freedom, a tethered DROP-IN gamma probe was designed. Here we present the first in vivo feasibility study of this technology in prostate cancer patients.

Methods

Ten patients scheduled for a sentinel node procedure received four injections into the prostate with (indocyanine green-)^99mTechnetium-nanocolloid and underwent preoperative imaging (lymphoscintigraphy and SPECT/CT). The DROP-IN probe was inserted via the assistant port, still permitting the insertion and usage of additional laparoscopic tools.

Results

The sentinel nodes were resected using the da Vinci® Si robot under guidance of DROP-IN gamma tracing and fluorescence imaging. The surgeon was able to independently maneuver the DROP-IN probe using the ProGrasp® forceps of the da Vinci® robot and distinguish sentinel nodes from background signal (such as the injection site).

Conclusions

Overall the DROP-IN design proves to be a valuable tool for robot-assisted radioguided surgery approaches.

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Title: Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation
Authors: Philippa Meershoek
Matthias N. van Oosterom
Hervé Simon
Laurent Mengus
Tobias Maurer
Pim J. van Leeuwen
Esther M. K. Wit
Henk G. van der Poel
Fijs W. B. van Leeuwen
Publication date: 01-01-2019
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 1/2019
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-018-4095-z

At a glance: The STEP trials

Springer Medicine

Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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