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Published in: Journal of Immigrant and Minority Health 1/2017

01-02-2017 | Original Paper

Risk Factors for Varicella Susceptibility Among Refugees to Toronto, Canada

Authors: Geneviève Cadieux, Vanessa Redditt, Daniela Graziano, Meb Rashid

Published in: Journal of Immigrant and Minority Health | Issue 1/2017

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Abstract

Several outbreaks of varicella have occurred among refugees. We aimed to estimate the prevalence of varicella susceptibility among refugees, and identify risk factors for varicella susceptibility. All refugees rostered at Crossroads Clinic in Toronto, Canada in 2011–2014 were included in our study. Varicella serology was assessed at the initial visit. Refugees’ age, sex, education, time since arrival, and climate and population density of birth country were abstracted from the chart. Multivariate logistic regression was used to identify risk factors for varicella susceptibility. 1063 refugees were rostered at Crossroads Clinic during the study; 7.9 % (95 % CI 6.1, 9.7) were susceptible to varicella. Tropical climate (OR 3.20, 95 % CI 1.53, 6.69) and younger age (ORper year of age 0.92, 95 % CI 0.88–0.96) were associated with increased varicella susceptibility. These risk factors for varicella susceptibility should be taken into account to maximize the cost-effectiveness of varicella prevention strategies among refugees.
Literature
1.
go back to reference Gushulak B, Pottie K, Hatcher Roberts J, Torres S, Des Meules M. Migration and health in Canada: health in the global village. CMAJ. 2011;183(12):E952–8.CrossRefPubMedPubMedCentral Gushulak B, Pottie K, Hatcher Roberts J, Torres S, Des Meules M. Migration and health in Canada: health in the global village. CMAJ. 2011;183(12):E952–8.CrossRefPubMedPubMedCentral
5.
go back to reference SanMartin C, Ross N. Experiencing difficulties accessing first-contact health services in Canada. Healthc Policy. 2006;1(2):103–19.PubMedPubMedCentral SanMartin C, Ross N. Experiencing difficulties accessing first-contact health services in Canada. Healthc Policy. 2006;1(2):103–19.PubMedPubMedCentral
6.
go back to reference DesMeules M, Gold J, McDermott S, Cao Z, Vissandjée B, Kliewer E, Mao Y. Disparities in mortality patterns among Canadian immigrants and refugees, 1980–1998: results of a national cohort study. J Immigr Health. 2005;7(4):221–32.CrossRefPubMed DesMeules M, Gold J, McDermott S, Cao Z, Vissandjée B, Kliewer E, Mao Y. Disparities in mortality patterns among Canadian immigrants and refugees, 1980–1998: results of a national cohort study. J Immigr Health. 2005;7(4):221–32.CrossRefPubMed
7.
go back to reference Sengupta N, Breuer J. A global perspective on the epidemiology and burden of varicella-zoster virus. Curr Pediatr Rev. 2009;5:207–28.CrossRef Sengupta N, Breuer J. A global perspective on the epidemiology and burden of varicella-zoster virus. Curr Pediatr Rev. 2009;5:207–28.CrossRef
8.
go back to reference Choo P, Donahue J, Manson J, Platt R. The epidemiology of varicella and its complications. J Infect Dis. 1995;172(3):706–12.CrossRefPubMed Choo P, Donahue J, Manson J, Platt R. The epidemiology of varicella and its complications. J Infect Dis. 1995;172(3):706–12.CrossRefPubMed
9.
go back to reference Galil K, Brown C, Lin F, Seward J. Hospitalizations for varicella in the United States, 1988 to 1999. Pediatr Infect Dis J. 2002;21(10):931–5.CrossRefPubMed Galil K, Brown C, Lin F, Seward J. Hospitalizations for varicella in the United States, 1988 to 1999. Pediatr Infect Dis J. 2002;21(10):931–5.CrossRefPubMed
10.
go back to reference Heymann DL. Varicella/Herpes Zoster. In: Heymann DL, editor. Control of communicable diseases manual. 20th ed. Washington, D.C.: American Public Health Association Press; 2015. p. 669–75.CrossRef Heymann DL. Varicella/Herpes Zoster. In: Heymann DL, editor. Control of communicable diseases manual. 20th ed. Washington, D.C.: American Public Health Association Press; 2015. p. 669–75.CrossRef
11.
go back to reference Barnett E, Christiansen D, Figueira M. Seroprevalence of measles, rubella, and varicella. Clin Infect Dis. 2002;15(35):403–8.CrossRef Barnett E, Christiansen D, Figueira M. Seroprevalence of measles, rubella, and varicella. Clin Infect Dis. 2002;15(35):403–8.CrossRef
12.
go back to reference Greenaway C, Boivin J, Cnossen S, Rossi C, Tapiero B, Schwartzman K, Olson S, Miller M. Risk factors for susceptibility to varicella in newly arrived adult migrants in Canada. Epidemiol Infect. 2014;142(8):1695–707.CrossRefPubMed Greenaway C, Boivin J, Cnossen S, Rossi C, Tapiero B, Schwartzman K, Olson S, Miller M. Risk factors for susceptibility to varicella in newly arrived adult migrants in Canada. Epidemiol Infect. 2014;142(8):1695–707.CrossRefPubMed
13.
go back to reference Okrainec K, Vissandjee B, DesMeules M, Holcroft C, Bartlett G, Greenaway C. Epidemiology of varicella infection among the foreign born in Quebec. Can J Infect Dis Med Microbiol. 2010;21(4):173–230. Okrainec K, Vissandjee B, DesMeules M, Holcroft C, Bartlett G, Greenaway C. Epidemiology of varicella infection among the foreign born in Quebec. Can J Infect Dis Med Microbiol. 2010;21(4):173–230.
14.
go back to reference Haas E, Dukhan L, Golstein L, Lyandres M, Gdalevich M. Use of vaccination in a large outbreak of primary varicella in a detention setting for African immigrants. Int Health. 2014;6:203–7.CrossRefPubMed Haas E, Dukhan L, Golstein L, Lyandres M, Gdalevich M. Use of vaccination in a large outbreak of primary varicella in a detention setting for African immigrants. Int Health. 2014;6:203–7.CrossRefPubMed
15.
go back to reference Centers for Disease Control and Prevention (CDC). Public Health Dispatch: varicella outbreaks among Mexican adults—Alabama, 2000. MMWR Morb Mortal Wkly Rep. 2000;49(32):735–6. Centers for Disease Control and Prevention (CDC). Public Health Dispatch: varicella outbreaks among Mexican adults—Alabama, 2000. MMWR Morb Mortal Wkly Rep. 2000;49(32):735–6.
16.
go back to reference Longfield JN, Winn RE, Gibson RL, Juchau SV, Hoffman PV. Varicella outbreaks among Army recruits in Puerto Rico. varicella susceptibility in a population from the tropics. Ann Intern Med. 1990;150(5):970–3.CrossRef Longfield JN, Winn RE, Gibson RL, Juchau SV, Hoffman PV. Varicella outbreaks among Army recruits in Puerto Rico. varicella susceptibility in a population from the tropics. Ann Intern Med. 1990;150(5):970–3.CrossRef
17.
go back to reference Gabutti G, Fedele A, Aprile V, Guido M, Lopalco P. Immigration flows and new epidemiological evidence in southern Italy. Vaccine. 2003;21(5–6):399–400.CrossRefPubMed Gabutti G, Fedele A, Aprile V, Guido M, Lopalco P. Immigration flows and new epidemiological evidence in southern Italy. Vaccine. 2003;21(5–6):399–400.CrossRefPubMed
18.
go back to reference Kjersem H, Jepsen S. Varicella among immigrants from the tropics, a health problem. Scand J Soc Med. 1990;18(3):171–4.PubMed Kjersem H, Jepsen S. Varicella among immigrants from the tropics, a health problem. Scand J Soc Med. 1990;18(3):171–4.PubMed
19.
go back to reference Deny P, Leport C, Jestin C. Chickenpox in one hundred Sri Lankan immigrants in France. Méd et Mal Infect. 1986;16:595–8.CrossRef Deny P, Leport C, Jestin C. Chickenpox in one hundred Sri Lankan immigrants in France. Méd et Mal Infect. 1986;16:595–8.CrossRef
21.
go back to reference Merrett P, Schwartzman K, Rivest P, Greenaway C. Strategies to prevent varicella among newly arrived adult immigrants and refugees: a cost-effectiveness analysis. Clin Infect Dis. 2007;15(44):1040–8.CrossRef Merrett P, Schwartzman K, Rivest P, Greenaway C. Strategies to prevent varicella among newly arrived adult immigrants and refugees: a cost-effectiveness analysis. Clin Infect Dis. 2007;15(44):1040–8.CrossRef
22.
go back to reference Christiansen D, Barnett E. Comparison of varicella history with presence of varicella antibodies in refugees. Vaccine. 2004;22:4233–7.CrossRefPubMed Christiansen D, Barnett E. Comparison of varicella history with presence of varicella antibodies in refugees. Vaccine. 2004;22:4233–7.CrossRefPubMed
23.
go back to reference MacMahon E, Brown LJ, Bexley S, Snashall DC, Patel D. Identification of potential candidates for varicella vaccination by history: questionnaire and seroprevalence study. BMJ. 2004;329(7465):551–2.CrossRefPubMedPubMedCentral MacMahon E, Brown LJ, Bexley S, Snashall DC, Patel D. Identification of potential candidates for varicella vaccination by history: questionnaire and seroprevalence study. BMJ. 2004;329(7465):551–2.CrossRefPubMedPubMedCentral
24.
go back to reference Mandal B, Mukherjee P, Murphy C, Mukherjee R, Naik TN. Adult susceptibility to varicella in the tropics is a rural phenomenon due to lack of previous exposure. J Infect Dis. 1998;178(Suppl 1):S52–4.CrossRefPubMed Mandal B, Mukherjee P, Murphy C, Mukherjee R, Naik TN. Adult susceptibility to varicella in the tropics is a rural phenomenon due to lack of previous exposure. J Infect Dis. 1998;178(Suppl 1):S52–4.CrossRefPubMed
27.
go back to reference Mishra AK, Gorbacheva O, Hasan MMT, Rimal N. Varicella (Chickenpox) outbreak in Bhutanese refugee camps in Eastern Nepal. Int J Infect Dis. 2010;14(supplement 1):e134.CrossRef Mishra AK, Gorbacheva O, Hasan MMT, Rimal N. Varicella (Chickenpox) outbreak in Bhutanese refugee camps in Eastern Nepal. Int J Infect Dis. 2010;14(supplement 1):e134.CrossRef
31.
go back to reference Pottie K, Greenaway C, Feightner J, Welch V, Swinkels H, Rashid M, Narasiah L, Kirmayer L, Ueffing E, MacDonald N, Hassan G, McNally M, Khan K, Buhrmann R, Dunn S, Dominic A, McCarthy A, Gagnon A, Rousseau C, Tugwell P, Coauthors of the Canadian Collaboration for Immigrant and Refugee Health. Evidence-based clinical guidelines for immigrants and refugees. CMAJ. 2011;183(12):E824–925.CrossRefPubMedPubMedCentral Pottie K, Greenaway C, Feightner J, Welch V, Swinkels H, Rashid M, Narasiah L, Kirmayer L, Ueffing E, MacDonald N, Hassan G, McNally M, Khan K, Buhrmann R, Dunn S, Dominic A, McCarthy A, Gagnon A, Rousseau C, Tugwell P, Coauthors of the Canadian Collaboration for Immigrant and Refugee Health. Evidence-based clinical guidelines for immigrants and refugees. CMAJ. 2011;183(12):E824–925.CrossRefPubMedPubMedCentral
32.
go back to reference Lebo EJ, Kruzson-Moran DM, Marin M, Bellini WJ, Schmid S, Bialek SR, Wallace GS, McLean HQ. Seroprevalence of measles, mumps, rubella and varicella antibodies in the United States population, 2009–2010. Open Forum Infect Dis. 2015;2(1):ofv006.CrossRefPubMedPubMedCentral Lebo EJ, Kruzson-Moran DM, Marin M, Bellini WJ, Schmid S, Bialek SR, Wallace GS, McLean HQ. Seroprevalence of measles, mumps, rubella and varicella antibodies in the United States population, 2009–2010. Open Forum Infect Dis. 2015;2(1):ofv006.CrossRefPubMedPubMedCentral
33.
go back to reference Leung J, Lopez A, Mitchell T, Weinberg M, Lee D, Thieme M, Schmid D, Bialek S. Seroprevalence of Varicella-Zoster virus in five US-Bound refugee populations. J Immigr Minor Health. 2015;17:310–3.CrossRefPubMedPubMedCentral Leung J, Lopez A, Mitchell T, Weinberg M, Lee D, Thieme M, Schmid D, Bialek S. Seroprevalence of Varicella-Zoster virus in five US-Bound refugee populations. J Immigr Minor Health. 2015;17:310–3.CrossRefPubMedPubMedCentral
34.
go back to reference Nysse LJ, Pinsky NA, Bratberg JP, Babar-Weber AY, Samuel TT, Krych EH, Ziegler AW, Jimale MA, Vierkant RA, Jacobson RN, Poland GA. Seroprevalence of antibody to varicella among Somali refugees. Mayo Clin Proc. 2007;82(2):175–80.CrossRefPubMed Nysse LJ, Pinsky NA, Bratberg JP, Babar-Weber AY, Samuel TT, Krych EH, Ziegler AW, Jimale MA, Vierkant RA, Jacobson RN, Poland GA. Seroprevalence of antibody to varicella among Somali refugees. Mayo Clin Proc. 2007;82(2):175–80.CrossRefPubMed
35.
go back to reference Figueira M, Christiansen D, Barnett E. Cost-effectiveness of serotesting compared with universal immunization for varicella in refugee children from six geographic regions. J Travel Med. 2003;10:203–7.CrossRefPubMed Figueira M, Christiansen D, Barnett E. Cost-effectiveness of serotesting compared with universal immunization for varicella in refugee children from six geographic regions. J Travel Med. 2003;10:203–7.CrossRefPubMed
36.
go back to reference Greenaway C, Boivin JF, Dongier P, Miller M, Schwartzman K. Susceptibility to vaccine-preventable disease in newly arrived immigrants and refugees to Montreal, Canada [abstract G-538-2004]. Program and abstracts of the 45th interscience conference on antimicrobial agents and chemotherapy (Washington, D.C.). 2004. Greenaway C, Boivin JF, Dongier P, Miller M, Schwartzman K. Susceptibility to vaccine-preventable disease in newly arrived immigrants and refugees to Montreal, Canada [abstract G-538-2004]. Program and abstracts of the 45th interscience conference on antimicrobial agents and chemotherapy (Washington, D.C.). 2004.
Metadata
Title
Risk Factors for Varicella Susceptibility Among Refugees to Toronto, Canada
Authors
Geneviève Cadieux
Vanessa Redditt
Daniela Graziano
Meb Rashid
Publication date
01-02-2017
Publisher
Springer US
Published in
Journal of Immigrant and Minority Health / Issue 1/2017
Print ISSN: 1557-1912
Electronic ISSN: 1557-1920
DOI
https://doi.org/10.1007/s10903-015-0313-y

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