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Journal of Cardiothoracic Surgery

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Open Access 01-12-2013 | Research article

Risk factors for early postoperative cognitive dysfunction after non-coronary bypass surgery in Chinese population

Authors: Tao Xu, Lulong Bo, Jiafeng Wang, Zhenzhen Zhao, Zhiyun Xu, Xiaoming Deng, Wenzhong Zhu

Published in: Journal of Cardiothoracic Surgery | Issue 1/2013

Abstract

Background

The present study was performed to investigate the incidence of early postoperative cognitive dysfunction (POCD) after non-coronary bypass surgery and the potential risk factors in Chinese population.

Methods

We performed a prospective study in a teaching tertiary hospital from May 2012 to August 2012. One hundred and seventy-six adult patients undergoing non-coronary bypass surgery were recruited. Mini-Mental State Examination (MMSE) score was evaluated before and 3 to 5 days after surgery. Patients with a MMSE score reduction of 2 was diagnosed with POCD.

Results

The general incidence of POCD was 33.0%, with no significant difference between the types of surgeries. In the univariate analysis, POCD associated factors included age, duration of surgery, anesthesia, cardiopulmonary bypass (CPB), cross-clamp and rewarming, and sevoflurane concentration. However, only age, cross-clamp duration and sevoflurane concentration were demonstrated to be independent risk factors for POCD.

Conclusion

Incidence of early POCD after non-coronary bypass surgery was relatively high in Chinese population. Advanced age, longer aortic cross-clamp duration and lower sevoflurane concentration was associated with a higher incidence of POCD.

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Title: Risk factors for early postoperative cognitive dysfunction after non-coronary bypass surgery in Chinese population
Authors: Tao Xu
Lulong Bo
Jiafeng Wang
Zhenzhen Zhao
Zhiyun Xu
Xiaoming Deng
Wenzhong Zhu
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: Journal of Cardiothoracic Surgery / Issue 1/2013
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/1749-8090-8-204

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Risk factors for early postoperative cognitive dysfunction after non-coronary bypass surgery in Chinese population

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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