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BMC Surgery
Published in: BMC Surgery 1/2017

Open Access 01-12-2017 | Research article

Risk factors for bile leakage after primary closure following laparoscopic common bile duct exploration: a retrospective cohort study

Authors: Dongbin Liu, Feng Cao, Jiafeng Liu, Dahua Xu, Yuehua Wang, Fei Li

Published in: BMC Surgery | Issue 1/2017

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Abstraction

Background

Primary closure following laparoscopic common bile duct exploration (LCBDE) has been widely adopted because of the efficacy and safety in treatment of common bile duct (CBD) stones. However, the risk factors for bile leakage, the most common complication after primary closure, has not been clarified yet.

Methods

A retrospective cohort study of patients who underwent LCBDE with primary closure after choledochotomy between Feb. 2012 and Jun. 2016 was performed. Risk factors for bile leakage were identified by logistic regression inculding demographic factors, preoperative condition and surgical details.

Results

Between Feb. 2012 and Jun. 2016, a total of 265 LCBDE procedures were applied in our hospital and 141 patients with primary closure were included in this study. Bile leakage occurred in 11.3% (16/141) of these patients, and happened more frequently in patients with slender CBD (<1 vs ≥1 cm, 31.6% vs 7.0%, p = 0.04) and those managed by inexperienced surgeons (initial 70 cases vs later cases, 17.1% vs 5.6%, p = 0.04). After multivariable regression, the diameter of CBD [OR 95% CI, 3.799 (1.081–13.349), p = 0.04] and experience of surgeons [OR 95% CI, 4.228 (1.330–13.438), p = 0.03] were significantly related to bile leakage.

Conclusion

Slender CBD and inexperienced surgeons were the high risk factors for bile leakage after primary closure following LCBDE.
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Metadata
Title
Risk factors for bile leakage after primary closure following laparoscopic common bile duct exploration: a retrospective cohort study
Authors
Dongbin Liu
Feng Cao
Jiafeng Liu
Dahua Xu
Yuehua Wang
Fei Li
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2017
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-016-0201-y

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