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01-02-2013 | Minisymposium

Rickets: Part I

Authors: Richard M. Shore, Russell W. Chesney

Published in: Pediatric Radiology | Issue 2/2013

Abstract

Rickets is characterized by impaired mineralization and ossification of the growth plates of growing children caused by a variety of disorders, the most frequent of which is nutritional deficiency of vitamin D. Despite ample knowledge of its etiology and the availability of cost-effective methods of preventing it, vitamin D deficiency rickets remains a significant problem in developing and developed countries. This two-part review covers the history, etiology, pathophysiology and clinical and radiographical findings of vitamin D deficiency rickets. Other less frequent causes of rickets and some of the disorders entering into the differential diagnoses of rickets are also considered. Controversial issues surrounding vitamin D deficiency include determination of what constitutes vitamin D sufficiency and the potential relationship between low levels of vitamin D metabolites in many individuals and unexplained fractures in infants.

As is customary in the United States and Canada, 25D levels are expressed in ng/ml. However, there is a trend toward using nmol/l; 1 ng/ml = 2.5 nmol/l

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Title: Rickets: Part I
Authors: Richard M. Shore
Russell W. Chesney
Publication date: 01-02-2013
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 2/2013
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-012-2532-x

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Rickets: Part I

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