Published in:
01-03-2005 | Letter to the Editor
Rhabdomyomatous mesenchymal hamartoma of oral cavity: an unusual location for such a rare lesion
Authors:
Gaetano Magro, Aurelio Di Benedetto, Giuseppe Sanges, Filippo Scalisi, Rita Alaggio
Published in:
Virchows Archiv
|
Issue 3/2005
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Excerpt
Sir, Rhabdomyomatous mesenchymal hamartoma (RMH) is a rare congenital lesion occurring in the skin, particularly of the face and neck [
4]. The term hamartoma has been histologically proven as a lesion composed of a disordered mixture of mature adipose, skeletal muscle tissue, adnexal structures and sometimes blood vessels and nerves [
4,
5]. Although RMH is usually a solitary lesion, it can be multiple and associated with uncommon congenital abnormalities [
5]. The etiology of RMH is still unclear, but it is likely that an aberrant embryological development or migration of mesodermally derived tissues due to micro-environmental modifications and/or genetic factors may play a pathogenetic role. …