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World Journal of Urology

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01-09-2021 | Original Article

Revolution spectral CT for urinary stone with a single/mixed composition in vivo: a large sample analysis

Authors: Xian Li, Lu-Ping Wang, Li-Li Ou, Xiao-Yan Huang, Qing-Si Zeng, Wen-Qi Wu

Published in: World Journal of Urology | Issue 9/2021

Abstract

Purpose

To analyze various compositions of urinary stones using revolution spectral CT (rapid kV switching dual-energy CT) in vivo.

Methods

202 patients with urinary stones underwent spectral CT before surgery. Zeff peak, overall scope and CT values were detected. Moreover, water/iodine attenuating material images were obtained. Removed stones were subjected to infrared spectroscopy after surgery. The results of infrared spectroscopy were compared with CT.

Results

28 stones (14.08%) with single composition, 165 stones with two mixed compositions (81.68%), and 9 stones with three mixed compositions (4.46%) were observed. When Zeff peaks of stones with single/mixed compositions were summarized together, 146 peaks of calcium oxalate monohydrate, 119 peaks of calcium oxalate dihydrate, 55 peaks of carbapatite, 38 peaks of urate, 16 peaks of struvite, and 11 peaks of brushite were totally observed. 93.8% of calcium oxalate monohydrate had Zeff peaks between 13.3 and 14.0. 91.6% of calcium oxalate dihydrate had peaks between 12.0 and 13.3. For carbapatite, 90.9% of stones had peaks from 14.0 to 15.0. A total of 94.8% of urate had peaks between 7.0 and 11.0. 93.8% of struvite had peaks between 11.0 and 13.0, and 90.9% of brushite had peaks between 12.0 and 14.0. Moreover, densities of urate, struvite and brushite were low density in iodine-based images and high-density in water-based images.

Conclusion

The in-vivo analysis of spectral CT in urinary stone revealed characteristics of different compositions, especially mixed compositions. An in-vivo predictive model may be constructed to distinguish stone compositions.

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Title: Revolution spectral CT for urinary stone with a single/mixed composition in vivo: a large sample analysis
Authors: Xian Li
Lu-Ping Wang
Li-Li Ou
Xiao-Yan Huang
Qing-Si Zeng
Wen-Qi Wu
Publication date: 01-09-2021
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 9/2021
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-021-03597-6

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Springer Medicine

Revolution spectral CT for urinary stone with a single/mixed composition in vivo: a large sample analysis

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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