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Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 11/2014

01-11-2014 | Case Reports / Case Series

Reversal of high spinal anesthesia with cerebrospinal lavage after inadvertent intrathecal injection of local anesthetic in an obstetric patient

Authors: Heather Y. Z. Ting, MD, Ban C. H. Tsui, MD

Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Issue 11/2014

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Abstract

Purpose

High or total spinal anesthesia commonly results from accidental placement of an epidural catheter in the intrathecal space with subsequent injection of excessive volumes of local anesthetic. Cerebrospinal lavage has been shown to be effective at reversing the effects of high/total spinal anesthesia but is rarely considered in obstetric cases. Here, we describe the use of cerebrospinal lavage to prevent potential complications from high/total spinal anesthesia after unintentional placement of an intrathecal catheter in a labouring obstetric patient.

Clinical features

A 34-yr-old female presented to the labour and delivery unit in active labour. Epidural anesthesia was initiated, and after the first bolus dose, the patient experienced lower extremity motor block and shortness of breath. A high spinal was confirmed, and cerebrospinal lavage was performed. In total, 40 mL of cerebrospinal fluid (CSF) were exchanged for an equal volume of normal saline. The patient’s breathing difficulties and motor block resolved quickly, and a new epidural catheter was placed after removal of the spinal catheter. Pain control was effective, and the patient delivered a healthy baby.

Conclusion

We show that exchange of CSF for normal saline can be used successfully to manage a high spinal in an obstetric patient. Our results suggest that CSF lavage could potentially be an important and helpful adjunct to the conventional supportive management of obstetric patients in the event of inadvertent high or total spinal anesthesia.
Literature
1.
go back to reference Jenkins JG. Some immediate serious complications of obstetric epidural analgesia and anaesthesia: a prospective study of 145,550 epidurals. Int J Obstet Anesth 2005; 14: 37-42.PubMedCrossRef Jenkins JG. Some immediate serious complications of obstetric epidural analgesia and anaesthesia: a prospective study of 145,550 epidurals. Int J Obstet Anesth 2005; 14: 37-42.PubMedCrossRef
2.
go back to reference Al Ferayan A, Russell NA, Al Wohaibi M, Awada A, Scherman B. Cerebrospinal fluid lavage in the treatment of inadvertent intrathecal vincristine injection. Childs Nerv Syst 1999; 15: 87-9.PubMedCrossRef Al Ferayan A, Russell NA, Al Wohaibi M, Awada A, Scherman B. Cerebrospinal fluid lavage in the treatment of inadvertent intrathecal vincristine injection. Childs Nerv Syst 1999; 15: 87-9.PubMedCrossRef
3.
go back to reference Covino BG, Marx GF, Finster M, Zsigmond EK. Prolonged sensory/motor deficits following inadvertent spinal anesthesia. Anesth Analg 1980; 59: 399-400.PubMedCrossRef Covino BG, Marx GF, Finster M, Zsigmond EK. Prolonged sensory/motor deficits following inadvertent spinal anesthesia. Anesth Analg 1980; 59: 399-400.PubMedCrossRef
4.
go back to reference Kaiser KG, Bainton CR. Treatment of intrathecal morphine overdose by aspiration of cerebrospinal fluid. Anesth Analg 1987; 66: 475-7.PubMedCrossRef Kaiser KG, Bainton CR. Treatment of intrathecal morphine overdose by aspiration of cerebrospinal fluid. Anesth Analg 1987; 66: 475-7.PubMedCrossRef
5.
go back to reference Southorn P, Vasdev GM, Chantigian RC, Lawson GM. Reducing the potential morbidity of an unintentional spinal anaesthetic by aspirating cerebrospinal fluid. Br J Anaesth 1996; 76: 467-9.PubMedCrossRef Southorn P, Vasdev GM, Chantigian RC, Lawson GM. Reducing the potential morbidity of an unintentional spinal anaesthetic by aspirating cerebrospinal fluid. Br J Anaesth 1996; 76: 467-9.PubMedCrossRef
6.
go back to reference Tsui BC, Malherbe S, Koller J, Aronyk K. Reversal of an unintentional spinal anesthetic by cerebrospinal lavage. Anesth Analg 2004; 98: 434-6.PubMedCrossRef Tsui BC, Malherbe S, Koller J, Aronyk K. Reversal of an unintentional spinal anesthetic by cerebrospinal lavage. Anesth Analg 2004; 98: 434-6.PubMedCrossRef
9.
go back to reference Introna RP, Blair JR, Neeld JB. What is the incidence of inadvertent dural puncture during epidural anesthesia in obstetrics? Anesthesiology 2012; 117: 686-7.PubMedCrossRef Introna RP, Blair JR, Neeld JB. What is the incidence of inadvertent dural puncture during epidural anesthesia in obstetrics? Anesthesiology 2012; 117: 686-7.PubMedCrossRef
10.
go back to reference Turnbull DK, Shepherd DB. Post-dural puncture headache: pathogenesis, prevention and treatment. Br J Anaesth 2003; 91: 718-29.PubMedCrossRef Turnbull DK, Shepherd DB. Post-dural puncture headache: pathogenesis, prevention and treatment. Br J Anaesth 2003; 91: 718-29.PubMedCrossRef
11.
go back to reference Abraham RA, Harris AP, Maxwell LG, Kaplow S. The efficacy of 1.5% lidocaine with 7.5% dextrose and epinephrine as an epidural test dose for obstetrics. Anesthesiology 1986; 64: 116-9.PubMedCrossRef Abraham RA, Harris AP, Maxwell LG, Kaplow S. The efficacy of 1.5% lidocaine with 7.5% dextrose and epinephrine as an epidural test dose for obstetrics. Anesthesiology 1986; 64: 116-9.PubMedCrossRef
12.
go back to reference Richardson MG, Lee AC, Wissler RN. High spinal anesthesia after epidural test dose administration in five obstetric patients. Reg Anesth 1996; 21: 119-23.PubMed Richardson MG, Lee AC, Wissler RN. High spinal anesthesia after epidural test dose administration in five obstetric patients. Reg Anesth 1996; 21: 119-23.PubMed
13.
go back to reference Steffek M, Owczuk R, Szlyk-Augustyn M, Lasinska-Kowara M, Wujtewicz M. Total spinal anaesthesia as a complication of local anaesthetic test-dose administration through an epidural catheter. Acta Anaesthesiol Scand 2004; 48: 1211-3.PubMedCrossRef Steffek M, Owczuk R, Szlyk-Augustyn M, Lasinska-Kowara M, Wujtewicz M. Total spinal anaesthesia as a complication of local anaesthetic test-dose administration through an epidural catheter. Acta Anaesthesiol Scand 2004; 48: 1211-3.PubMedCrossRef
14.
go back to reference Ben-David B, Rawa R. Complications of neuraxial blockade. Anesthesiol Clin North America 2002; 20: 669-93.PubMedCrossRef Ben-David B, Rawa R. Complications of neuraxial blockade. Anesthesiol Clin North America 2002; 20: 669-93.PubMedCrossRef
15.
go back to reference Davies JM, Posner KL, Lee LA, Cheney FW, Domino KB. Liability associated with obstetric anesthesia: a closed claims analysis. Anesthesiology 2009; 110: 131-9.PubMedCrossRef Davies JM, Posner KL, Lee LA, Cheney FW, Domino KB. Liability associated with obstetric anesthesia: a closed claims analysis. Anesthesiology 2009; 110: 131-9.PubMedCrossRef
16.
go back to reference Oka K, Yamamoto M, Nonaka T, Tomonaga M. The significance of artificial cerebrospinal fluid as perfusate and endoneurosurgery. Neurosurgery 1996; 38: 733-6.PubMedCrossRef Oka K, Yamamoto M, Nonaka T, Tomonaga M. The significance of artificial cerebrospinal fluid as perfusate and endoneurosurgery. Neurosurgery 1996; 38: 733-6.PubMedCrossRef
17.
go back to reference Bergsneider M. Endoscopic removal of cysticercal cysts within the fourth ventricle. Technical note. J Neurosurg 1999; 91: 340-5.PubMedCrossRef Bergsneider M. Endoscopic removal of cysticercal cysts within the fourth ventricle. Technical note. J Neurosurg 1999; 91: 340-5.PubMedCrossRef
18.
go back to reference Carpenter RL, Hogan QH, Liu SS, Crane B, Moore J. Lumbosacral cerebrospinal fluid volume is the primary determinant of sensory block extent and duration during spinal anesthesia. Anesthesiology 1998; 89: 24-9.PubMedCrossRef Carpenter RL, Hogan QH, Liu SS, Crane B, Moore J. Lumbosacral cerebrospinal fluid volume is the primary determinant of sensory block extent and duration during spinal anesthesia. Anesthesiology 1998; 89: 24-9.PubMedCrossRef
19.
go back to reference Hogan QH, Prost R, Kulier A, Taylor ML, Liu S, Mark L. Magnetic resonance imaging of cerebrospinal fluid volume and the influence of body habitus and abdominal pressure. Anesthesiology 1996; 84: 1341-9.PubMedCrossRef Hogan QH, Prost R, Kulier A, Taylor ML, Liu S, Mark L. Magnetic resonance imaging of cerebrospinal fluid volume and the influence of body habitus and abdominal pressure. Anesthesiology 1996; 84: 1341-9.PubMedCrossRef
20.
go back to reference Sullivan JT, Grouper S, Walker MT, Parrish TB, McCarthy RJ, Wong CA. Lumbosacral cerebrospinal fluid volume in humans using three-dimensional magnetic resonance imaging. Anesth Analg 2006; 103: 1306-10.PubMedCrossRef Sullivan JT, Grouper S, Walker MT, Parrish TB, McCarthy RJ, Wong CA. Lumbosacral cerebrospinal fluid volume in humans using three-dimensional magnetic resonance imaging. Anesth Analg 2006; 103: 1306-10.PubMedCrossRef
21.
go back to reference Onuki E, Higuchi H, Takagi S, et al. Gestation-related reduction in lumbar cerebrospinal fluid volume and dural sac surface area. Anesth Analg 2010; 110: 148-53.PubMedCrossRef Onuki E, Higuchi H, Takagi S, et al. Gestation-related reduction in lumbar cerebrospinal fluid volume and dural sac surface area. Anesth Analg 2010; 110: 148-53.PubMedCrossRef
22.
go back to reference Lee DS, Bui T, Ferrarese J, Richardson PK. Cauda equina syndrome after incidental total spinal anesthesia with 2% lidocaine. J Clin Anesth 1998; 10: 66-9.PubMedCrossRef Lee DS, Bui T, Ferrarese J, Richardson PK. Cauda equina syndrome after incidental total spinal anesthesia with 2% lidocaine. J Clin Anesth 1998; 10: 66-9.PubMedCrossRef
23.
go back to reference Ravindran RS, Bond VK, Tasch MD, Gupta CD, Luerssen TG. Prolonged neural blockade following regional analgesia with 2-chloroprocaine. Anesth Analg 1980; 59: 447-51.PubMed Ravindran RS, Bond VK, Tasch MD, Gupta CD, Luerssen TG. Prolonged neural blockade following regional analgesia with 2-chloroprocaine. Anesth Analg 1980; 59: 447-51.PubMed
24.
go back to reference Rose JB. Spinal cord injury in a child after single-shot epidural anesthesia. Anesth Analg 2003; 96: 3-6.PubMed Rose JB. Spinal cord injury in a child after single-shot epidural anesthesia. Anesth Analg 2003; 96: 3-6.PubMed
25.
go back to reference Litz RJ, Popp M, Stehr SN, Koch T. Successful resuscitation of a patient with ropivacaine-induced asystole after axillary plexus block using lipid infusion. Anaesthesia 2006; 61: 800-1.PubMedCrossRef Litz RJ, Popp M, Stehr SN, Koch T. Successful resuscitation of a patient with ropivacaine-induced asystole after axillary plexus block using lipid infusion. Anaesthesia 2006; 61: 800-1.PubMedCrossRef
26.
go back to reference McCutchen T, Gerancher JC. Early intralipid therapy may have prevented bupivacaine-associated cardiac arrest. Reg Anesth Pain Med 2008; 33: 178-80.PubMedCrossRef McCutchen T, Gerancher JC. Early intralipid therapy may have prevented bupivacaine-associated cardiac arrest. Reg Anesth Pain Med 2008; 33: 178-80.PubMedCrossRef
27.
go back to reference Rosenblatt MA, Abel M, Fischer GW, Itzkovich CJ, Eisenkraft JB. Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest. Anesthesiology 2006; 105: 217-8.PubMedCrossRef Rosenblatt MA, Abel M, Fischer GW, Itzkovich CJ, Eisenkraft JB. Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest. Anesthesiology 2006; 105: 217-8.PubMedCrossRef
Metadata
Title
Reversal of high spinal anesthesia with cerebrospinal lavage after inadvertent intrathecal injection of local anesthetic in an obstetric patient
Authors
Heather Y. Z. Ting, MD
Ban C. H. Tsui, MD
Publication date
01-11-2014
Publisher
Springer US
Published in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Issue 11/2014
Print ISSN: 0832-610X
Electronic ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-014-0219-5

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