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Published in: Neurosurgical Review 1/2018

01-01-2018 | Original Article

Retrospective analysis of cervical corpectomies: implant-related complications of one- and two-level corpectomies in 45 patients

Authors: Sebastian Hartmann, P. Kavakebi, C. Wipplinger, A. Tschugg, P. P. Girod, S. Lener, C. Thomé

Published in: Neurosurgical Review | Issue 1/2018

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Abstract

Cervical corpectomies are increasingly used to treat degenerative, metastatic, inflammatory and traumatic multisegmental diseases. The postoperative results are thought to correlate mainly with the number of resected vertebral bodies. Thus, the aim of the study was to analyse complications and early outcome of these procedures to document the implant-related complications in order to set up a prospective clinical trial. Forty-five patients, who were treated in our department from 2011 to 2014 and who were available for a minimum follow-up of 1 year, were consecutively included in this retrospective evaluation. The median age was 61 (±11) years with a female to male sex ratio of 19 to 26, respectively. In these patients, cervical corpectomies (one-, two- and three-level procedures) were performed. The average number of resected levels was 1.2 levels. The intraoperative loss of blood (LOB), the red cell transfusions (rcT), the length of operation (LOO) and the usage of drains were investigated and correlated with intra- and postoperative complications. The mean LOO was 244 min (±68) with a mean LOB of 511 ml (±531). The overall complication rate was 22.9% (10 patients). Six patients (13.3%) had implant-related complications due to loosening and toggling of the screws and/or cage subsidence. Two patients (4.4%) had a postoperative haematoma and another two patients (4.4%) suffered from neurological deterioration due to an ongoing and severe myelopathic syndrome. All these patients received revision surgery. The average time from the first to revision surgery was 90 days. Cervical corpectomies still remain procedures with a high complication rate mainly represented by implant-related failures. These implant-related complications range from screw/plate loosening or toggling to graft dislocation with subsidence and might be associated with constructs extended to the C7 vertebral body. In our study population, the rate of implant failure was comparable to the literature, but not obviously correlated with the number of vertebral bodies resected. This may be attributed to the different disease entities. Thus, our results support the use of circumferential approaches for selected instability scenarios (metastatic or inflammatory diseases, kyphosis, osteoporosis, etc.) of one- and two-level corpectomies.
Literature
5.
go back to reference Kristof RA, Kiefer T, Thudium M, Ringel F, Stoffel M, Kovacs A, Mueller CA (2009) Comparison of ventral corpectomy and plate-screw-instrumented fusion with dorsal laminectomy and rod-screw-instrumented fusion for treatment of at least two vertebral-level spondylotic cervical myelopathy. Eur Spine J 18:1951–1956. doi:10.1007/s00586-009-1110-x CrossRefPubMedPubMedCentral Kristof RA, Kiefer T, Thudium M, Ringel F, Stoffel M, Kovacs A, Mueller CA (2009) Comparison of ventral corpectomy and plate-screw-instrumented fusion with dorsal laminectomy and rod-screw-instrumented fusion for treatment of at least two vertebral-level spondylotic cervical myelopathy. Eur Spine J 18:1951–1956. doi:10.​1007/​s00586-009-1110-x CrossRefPubMedPubMedCentral
6.
go back to reference Vaccaro AR, Falatyn SP, Scuderi GJ, Eismont FJ, McGuire RA, Singh K, Garfin SR (1998) Early failure of long segment anterior cervical plate fixation. J Spinal Disord 11:410–415PubMed Vaccaro AR, Falatyn SP, Scuderi GJ, Eismont FJ, McGuire RA, Singh K, Garfin SR (1998) Early failure of long segment anterior cervical plate fixation. J Spinal Disord 11:410–415PubMed
8.
go back to reference Thalgott JS, Xiongsheng C, Giuffre JM (2003) Single stage anterior cervical reconstruction with titanium mesh cages, local bone graft, and anterior plating. Spine J 3:294–300CrossRefPubMed Thalgott JS, Xiongsheng C, Giuffre JM (2003) Single stage anterior cervical reconstruction with titanium mesh cages, local bone graft, and anterior plating. Spine J 3:294–300CrossRefPubMed
9.
go back to reference Daubs MD (2005) Early failures following cervical corpectomy reconstruction with titanium mesh cages and anterior plating. Spine (Phila Pa 1976) 30:1402–1406CrossRef Daubs MD (2005) Early failures following cervical corpectomy reconstruction with titanium mesh cages and anterior plating. Spine (Phila Pa 1976) 30:1402–1406CrossRef
10.
go back to reference Panjabi MM, Isomi T, Wang JL (1999) Loosening at the screw-vertebra junction in multilevel anterior cervical plate constructs. Spine (Phila Pa 1976) 24:2383–2388CrossRef Panjabi MM, Isomi T, Wang JL (1999) Loosening at the screw-vertebra junction in multilevel anterior cervical plate constructs. Spine (Phila Pa 1976) 24:2383–2388CrossRef
11.
go back to reference Sevki K, Mehmet T, Ufuk T, Azmi H, Mercan S, Erkal B (2004) Results of surgical treatment for degenerative cervical myelopathy: anterior cervical corpectomy and stabilization. Spine (Phila Pa 1976) 29:2493–2500CrossRef Sevki K, Mehmet T, Ufuk T, Azmi H, Mercan S, Erkal B (2004) Results of surgical treatment for degenerative cervical myelopathy: anterior cervical corpectomy and stabilization. Spine (Phila Pa 1976) 29:2493–2500CrossRef
12.
go back to reference Setzer M, Eleraky M, Johnson WM, Aghayev K, Tran ND, Vrionis FD (2012) Biomechanical comparison of anterior cervical spine instrumentation techniques with and without supplemental posterior fusion after different corpectomy and discectomy combinations: laboratory investigation. J Neurosurg Spine 16:579–584. doi:10.3171/2012.2.SPINE11611 CrossRefPubMed Setzer M, Eleraky M, Johnson WM, Aghayev K, Tran ND, Vrionis FD (2012) Biomechanical comparison of anterior cervical spine instrumentation techniques with and without supplemental posterior fusion after different corpectomy and discectomy combinations: laboratory investigation. J Neurosurg Spine 16:579–584. doi:10.​3171/​2012.​2.​SPINE11611 CrossRefPubMed
13.
go back to reference Acosta FL, Aryan HE, Chou D, Ames CP (2008) Long-term biomechanical stability and clinical improvement after extended multilevel corpectomy and circumferential reconstruction of the cervical spine using titanium mesh cages. J Spinal Disord Tech 21:165–174. doi:10.1097/BSD.0b013e3180654205 CrossRefPubMed Acosta FL, Aryan HE, Chou D, Ames CP (2008) Long-term biomechanical stability and clinical improvement after extended multilevel corpectomy and circumferential reconstruction of the cervical spine using titanium mesh cages. J Spinal Disord Tech 21:165–174. doi:10.​1097/​BSD.​0b013e3180654205​ CrossRefPubMed
14.
go back to reference Yan D, Wang Z, Deng S, Li J, Soo C (2011) Anterior corpectomy and reconstruction with titanium mesh cage and dynamic cervical plate for cervical spondylotic myelopathy in elderly osteoporosis patients. Arch Orthop Trauma Surg 131:1369–1374. doi:10.1007/s00402-011-1317-2 CrossRefPubMed Yan D, Wang Z, Deng S, Li J, Soo C (2011) Anterior corpectomy and reconstruction with titanium mesh cage and dynamic cervical plate for cervical spondylotic myelopathy in elderly osteoporosis patients. Arch Orthop Trauma Surg 131:1369–1374. doi:10.​1007/​s00402-011-1317-2 CrossRefPubMed
15.
go back to reference Eleraky MA, Llanos C, Sonntag VK (1999) Cervical corpectomy: report of 185 cases and review of the literature. J Neurosurg 90:35–41CrossRefPubMed Eleraky MA, Llanos C, Sonntag VK (1999) Cervical corpectomy: report of 185 cases and review of the literature. J Neurosurg 90:35–41CrossRefPubMed
16.
17.
go back to reference Yamagata T, Takami T, Uda T, Ikeda H, Nagata T, Sakamoto S et al (2012) Outcomes of contemporary use of rectangular titanium stand-alone cages in anterior cervical discectomy and fusion: cage subsidence and cervical alignment. J Clin Neurosci 19:1673–1678. doi:10.1016/j.jocn.2011.11.043 CrossRefPubMed Yamagata T, Takami T, Uda T, Ikeda H, Nagata T, Sakamoto S et al (2012) Outcomes of contemporary use of rectangular titanium stand-alone cages in anterior cervical discectomy and fusion: cage subsidence and cervical alignment. J Clin Neurosci 19:1673–1678. doi:10.​1016/​j.​jocn.​2011.​11.​043 CrossRefPubMed
19.
go back to reference Waschke A, Walter J, Duenisch P, Kalff R, Ewald C (2013) Anterior cervical intercorporal fusion in patients with osteoporotic or tumorous fractures using a cement augmented cervical plate system: first results of a prospective single-center study. J Spinal Disord Tech 26:E112–E117. doi:10.1097/BSD.0b013e3182764b37 CrossRefPubMed Waschke A, Walter J, Duenisch P, Kalff R, Ewald C (2013) Anterior cervical intercorporal fusion in patients with osteoporotic or tumorous fractures using a cement augmented cervical plate system: first results of a prospective single-center study. J Spinal Disord Tech 26:E112–E117. doi:10.​1097/​BSD.​0b013e3182764b37​ CrossRefPubMed
20.
go back to reference Koller H, Schmidt R, Mayer M, Hitzl W, Zenner J, Midderhoff S et al (2010) The stabilizing potential of anterior, posterior and combined techniques for the reconstruction of a 2-level cervical corpectomy model: biomechanical study and first results of ATPS prototyping. Eur Spine J 19:2137–2148. doi:10.1007/s00586-010-1503-x CrossRefPubMedPubMedCentral Koller H, Schmidt R, Mayer M, Hitzl W, Zenner J, Midderhoff S et al (2010) The stabilizing potential of anterior, posterior and combined techniques for the reconstruction of a 2-level cervical corpectomy model: biomechanical study and first results of ATPS prototyping. Eur Spine J 19:2137–2148. doi:10.​1007/​s00586-010-1503-x CrossRefPubMedPubMedCentral
21.
go back to reference Koller H, Schmoelz W, Zenner J, Auffarth A, Resch H, Hitzl W et al (2015) Construct stability of an instrumented 2-level cervical corpectomy model following fatigue testing: biomechanical comparison of circumferential antero-posterior instrumentation versus a novel anterior-only transpedicular screw-plate fixation technique. Eur Spine J 24:2848–2856. doi:10.1007/s00586-015-3770-z CrossRefPubMed Koller H, Schmoelz W, Zenner J, Auffarth A, Resch H, Hitzl W et al (2015) Construct stability of an instrumented 2-level cervical corpectomy model following fatigue testing: biomechanical comparison of circumferential antero-posterior instrumentation versus a novel anterior-only transpedicular screw-plate fixation technique. Eur Spine J 24:2848–2856. doi:10.​1007/​s00586-015-3770-z CrossRefPubMed
22.
23.
go back to reference Aramomi M, Masaki Y, Koshizuka S, Kadota R, Okawa A, Koda M, Yamazaki M (2008): Anterior pedicle screw fixation for multilevel cervical corpectomy and spinal fusion. Acta Neurochir 150:575–582; discussion 582. doi:10.1007/s00701-008-1574-1 CrossRefPubMed Aramomi M, Masaki Y, Koshizuka S, Kadota R, Okawa A, Koda M, Yamazaki M (2008): Anterior pedicle screw fixation for multilevel cervical corpectomy and spinal fusion. Acta Neurochir 150:575–582; discussion 582. doi:10.​1007/​s00701-008-1574-1 CrossRefPubMed
24.
go back to reference Hartmann S, Thomé C, Tschugg A, Paesold J, Kavakebi P, Schmölz W (2017) Cement-augmented screws in a cervical two-level corpectomy with anterior titanium mesh cage reconstruction: a biomechanical study. Eur Spine J. doi:10.1007/s00586-017-4951-8 Hartmann S, Thomé C, Tschugg A, Paesold J, Kavakebi P, Schmölz W (2017) Cement-augmented screws in a cervical two-level corpectomy with anterior titanium mesh cage reconstruction: a biomechanical study. Eur Spine J. doi:10.​1007/​s00586-017-4951-8
Metadata
Title
Retrospective analysis of cervical corpectomies: implant-related complications of one- and two-level corpectomies in 45 patients
Authors
Sebastian Hartmann
P. Kavakebi
C. Wipplinger
A. Tschugg
P. P. Girod
S. Lener
C. Thomé
Publication date
01-01-2018
Publisher
Springer Berlin Heidelberg
Published in
Neurosurgical Review / Issue 1/2018
Print ISSN: 0344-5607
Electronic ISSN: 1437-2320
DOI
https://doi.org/10.1007/s10143-017-0854-8

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