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Published in: Langenbeck's Archives of Surgery 7/2017

01-11-2017 | ORIGINAL ARTICLE

Results of surgical treatment for jejunal Crohn’s disease: choice between resection, strictureplasty, and combined treatment

Authors: Francesco Tonelli, Giovanni Alemanno, Carmela Di Martino, Adriana Focardi, Giorgio Gronchi, Francesco Giudici

Published in: Langenbeck's Archives of Surgery | Issue 7/2017

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Abstract

Purpose

The jejunum is a relatively uncommon localization of Crohn’s disease (CD) compared to the terminal ileum or the large bowel. The type of surgery and the short and long-term results after surgery have not been extensively investigated. A review of patients who underwent surgery for jejunal CD in our center was examined.

Methods

Between 1986 and 2011, 110 patients underwent surgery for jejunal CD. Thirty patients (27.3 %) were surgically treated with resection, 29 patients (26.4 %) with one or more strictureplasties, and 51 patients (46.3 %) with both a resection and one or more strictureplasties.

Results

There was no statistical difference in terms of short-term postoperative complications between patients operated with three different options (p = 0.72). Patients were followed up for a period ranging from 2 to 18 years (mean 11 years). During this period, 42 patients had no CD recurrence, 11 patients had medical recurrences only, while 57 patients had surgical recurrences, too. There was no statistical difference in terms of medical and surgical recurrence between the three types of surgical procedures employed (p = 0.24) and between smokers and non-smokers. The recurrent CD was prevalently treated with strictureplasty.

Conclusions

The most frequently employed surgery for the treatment of jejunal CD is a combined type of treatment, i.e., resection of the most affected tract and strictureplasty of the residual strictures. This approach does not imply an increased risk of postoperative complications and recurrence and can reduce the risk of the short bowel syndrome.
Literature
5.
go back to reference Freeman HJ (2005) Long-term clinical behavior of jejunoileal involvement in Crohn’s disease. Can J Gastroenterol 19:575–578CrossRefPubMed Freeman HJ (2005) Long-term clinical behavior of jejunoileal involvement in Crohn’s disease. Can J Gastroenterol 19:575–578CrossRefPubMed
7.
go back to reference Fanucci A, Cerro P, Fanucci E (1988) Normal small-bowel measurements by enteroclysis. Scand J Gastroenterol 23:574–576CrossRefPubMed Fanucci A, Cerro P, Fanucci E (1988) Normal small-bowel measurements by enteroclysis. Scand J Gastroenterol 23:574–576CrossRefPubMed
8.
go back to reference Gregg JB, Weisser JR (1950) Isolated jejunal involvement in regional enteritis. Am J Surg 80:873–882CrossRefPubMed Gregg JB, Weisser JR (1950) Isolated jejunal involvement in regional enteritis. Am J Surg 80:873–882CrossRefPubMed
9.
go back to reference Froehlich AL (1950) Case of Crohn’s enteritis of jejunum II; pathogenesis. Acta Gastroenterol Belg 13:1130–1134PubMed Froehlich AL (1950) Case of Crohn’s enteritis of jejunum II; pathogenesis. Acta Gastroenterol Belg 13:1130–1134PubMed
10.
go back to reference Crismer R (1950) Crohn’s disease localized in the jejunum, accompanied by chronic pancreatitis and achrestic anemia. Acta Gastroenterol Belg 13:1135–1140PubMed Crismer R (1950) Crohn’s disease localized in the jejunum, accompanied by chronic pancreatitis and achrestic anemia. Acta Gastroenterol Belg 13:1135–1140PubMed
11.
go back to reference Rutledge BJ, Mulvey BE (1953) Regional enteritis isolated to the jejunum; a report of two cases. J Okla State Med Assoc 46:4–5PubMed Rutledge BJ, Mulvey BE (1953) Regional enteritis isolated to the jejunum; a report of two cases. J Okla State Med Assoc 46:4–5PubMed
12.
go back to reference De Campos HA, Pontes JF, Cutait DE, De Lima MT (1953) Crohn’s segmental jejunitis. Rev Paul Med 42:351–356PubMed De Campos HA, Pontes JF, Cutait DE, De Lima MT (1953) Crohn’s segmental jejunitis. Rev Paul Med 42:351–356PubMed
13.
go back to reference Deloyers L, Le Cluyse R (1959) Quadruple jejunal localization of Crohn’s disease in an aged patient. Acta Gastroenterol Belg 22:244–248PubMed Deloyers L, Le Cluyse R (1959) Quadruple jejunal localization of Crohn’s disease in an aged patient. Acta Gastroenterol Belg 22:244–248PubMed
14.
go back to reference Cooke WT, Swan CH (1974) Diffuse jejuno-ileitis of Crohn’s disease. Q J Med 43:583–601PubMed Cooke WT, Swan CH (1974) Diffuse jejuno-ileitis of Crohn’s disease. Q J Med 43:583–601PubMed
15.
go back to reference Marion JF, Lachman P, Greenstein AJ, Sachar DB (1995) Rarity of fistulas in Crohn’s disease of the jejunum. Inflamm Bowel Dis 1:34–36PubMed Marion JF, Lachman P, Greenstein AJ, Sachar DB (1995) Rarity of fistulas in Crohn’s disease of the jejunum. Inflamm Bowel Dis 1:34–36PubMed
16.
go back to reference Marshak RH, Wolf BS (1953) Chronic ulcerative granulomatous jejunitis and ileojejunitis. Am J Roentgenol Radium Therapy, Nucl Med 70:93–113 Marshak RH, Wolf BS (1953) Chronic ulcerative granulomatous jejunitis and ileojejunitis. Am J Roentgenol Radium Therapy, Nucl Med 70:93–113
19.
go back to reference Hurst RD, Molinari M, Chung TP, et al. (1997) Prospective study of the features, indications, and surgical treatment in 513 consecutive patients affected by Crohn’s disease. Surgery 122:661–667 discussion 667–8CrossRefPubMed Hurst RD, Molinari M, Chung TP, et al. (1997) Prospective study of the features, indications, and surgical treatment in 513 consecutive patients affected by Crohn’s disease. Surgery 122:661–667 discussion 667–8CrossRefPubMed
20.
go back to reference Chardavoyne R, Flint GW, Pollack S, Wise L (1986) Factors affecting recurrence following resection for Crohn’s disease. Dis Colon rectum 29:495–502 Chardavoyne R, Flint GW, Pollack S, Wise L (1986) Factors affecting recurrence following resection for Crohn’s disease. Dis Colon rectum 29:495–502
21.
go back to reference Fazio VW, Marchetti F, Church M, et al. (1996) Effect of resection margins on the recurrence of Crohn’s disease in the small bowel. A randomized controlled trial. Ann Surg 224:563–571 discussion 571–3CrossRefPubMedPubMedCentral Fazio VW, Marchetti F, Church M, et al. (1996) Effect of resection margins on the recurrence of Crohn’s disease in the small bowel. A randomized controlled trial. Ann Surg 224:563–571 discussion 571–3CrossRefPubMedPubMedCentral
22.
go back to reference Yamamoto T, Bain IM, Allan RN, Keighley MR (1999) An audit of strictureplasty for small-bowel Crohn’s disease. Dis Colon rectum 42:797–803 Yamamoto T, Bain IM, Allan RN, Keighley MR (1999) An audit of strictureplasty for small-bowel Crohn’s disease. Dis Colon rectum 42:797–803
25.
go back to reference Cottone M, Rosselli M, Orlando A, et al. (1994) Smoking habits and recurrence in Crohn’s disease. Gastroenterology 106:643–648CrossRefPubMed Cottone M, Rosselli M, Orlando A, et al. (1994) Smoking habits and recurrence in Crohn’s disease. Gastroenterology 106:643–648CrossRefPubMed
26.
go back to reference Lazarev M, Huang C, Bitton A, et al. (2013) Relationship between proximal Crohn’s disease location and disease behavior and surgery: a cross-sectional study of the IBD genetics consortium. Am J Gastroenterol 108:106–112. doi:10.1038/ajg.2012.389 CrossRefPubMed Lazarev M, Huang C, Bitton A, et al. (2013) Relationship between proximal Crohn’s disease location and disease behavior and surgery: a cross-sectional study of the IBD genetics consortium. Am J Gastroenterol 108:106–112. doi:10.​1038/​ajg.​2012.​389 CrossRefPubMed
Metadata
Title
Results of surgical treatment for jejunal Crohn’s disease: choice between resection, strictureplasty, and combined treatment
Authors
Francesco Tonelli
Giovanni Alemanno
Carmela Di Martino
Adriana Focardi
Giorgio Gronchi
Francesco Giudici
Publication date
01-11-2017
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 7/2017
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-016-1497-x

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