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Published in: CardioVascular and Interventional Radiology 5/2011

01-10-2011 | Clinical Investigation

Results of a Seven-Year, Single-Centre Experience of the Long-Term Outcomes of Bovine Ureter Grafts Used as Novel Conduits for Haemodialysis Fistulas

Authors: Neelan Das, Mark J. Bratby, Vivek Shrivastava, Alison J. Cornall, Christopher R. Darby, Philip Boardman, Susan Anthony, Raman Uberoi

Published in: CardioVascular and Interventional Radiology | Issue 5/2011

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Abstract

Purpose

To report the long-term outcomes of bovine ureter grafts as novel conduits for haemodialysis fistulas.

Materials and Methods

Thirty-five patients underwent placement of a total of 40 SynerGraft 100 (SG100; CryoLife Europa®, Guildford, UK) bovine ureter grafts between April 2002 and February 2009. Prospective data were collected on all patients, including active surveillance with blood flow studies and 6-monthly duplex ultrasound studies. Main outcome measures were primary and secondary patency rates.

Results

Mean follow-up time was 97 weeks (range 4–270). Thirteen patients died from unrelated causes during the study period; 12 of these patients had a functioning graft at the time of death. Five patients underwent transplantation, and all had a functioning graft at transplantation. Twelve patients had a functioning graft at the end of the study period. One hundred and ten stenoses were detected, and 97 venoplasty procedures were performed. Of the stenoses, 41.8% were located at the venous anastomosis, 12.7% within the graft, 17.3% in the outflow veins, and 28.1% in central veins. No arterial stenoses were detected. Primary patency rates were 53% at 6 months and 14% at 1 year. Secondary patency rates were 81% at 6 months, 75% at 1 year, and 56% at 2 years.

Conclusions

Active surveillance and intervention was able to achieve satisfactory long-term secondary patency for these novel conduits compared with those made of PTFE seen in other studies [1].
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Metadata
Title
Results of a Seven-Year, Single-Centre Experience of the Long-Term Outcomes of Bovine Ureter Grafts Used as Novel Conduits for Haemodialysis Fistulas
Authors
Neelan Das
Mark J. Bratby
Vivek Shrivastava
Alison J. Cornall
Christopher R. Darby
Philip Boardman
Susan Anthony
Raman Uberoi
Publication date
01-10-2011
Publisher
Springer-Verlag
Published in
CardioVascular and Interventional Radiology / Issue 5/2011
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-011-0096-z

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