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Open Access 01-12-2020 | Restless Legs Syndrome | Research article

The prevalence of Restless Legs Syndrome/Willis-ekbom disease (RLS/WED) in the third trimester of pregnancy: a systematic review

Authors: Niloofar Darvishi, Alireza Daneshkhah, Behnam Khaledi-Paveh, Aliakbar Vaisi-Raygani, Masoud Mohammadi, Nader Salari, Fateme Darvishi, Alireza Abdi, Rostam Jalali

Published in: BMC Neurology | Issue 1/2020

Abstract

Background

RLS is known as one of the most common movement disorders during pregnancy, which is most aggravated in the third trimester of pregnancy and can affect up to one-third of pregnant women. This study intends to determine the total prevalence of RLS in the third trimester of pregnancy through a systematic review.

Methods

The present study was conducted via meta-analysis method up to 2019. The papers related to the subject of interest were obtained through searching in SID, MagIran, IranDoc, Scopus, Embase, Web of Science (ISI), PubMed, Science Direct, and Google Scholar databases. Heterogeneity of the studies was examined via I² index, and the data were analyzed in Comprehensive meta-analysis software.

Results

In investigating 10 papers capturing 2431 subjects within the age range of 25–39 years, the total prevalence of RLS in the third trimester of pregnancy based on meta-analysis was obtained as 22.9% (95% CI: 14.7–33.8%). Further, as the sample size increased, the RLS prevalence diminished, while with increase in years, this prevalence increased, where this difference was statistically significant (P < 0.05).

Conclusion

Prevalence of RLS in the third trimester of pregnancy is high, healthcare policymakers should organize educational classes to improve the life dimensions among this group of pregnant women.

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Title: The prevalence of Restless Legs Syndrome/Willis-ekbom disease (RLS/WED) in the third trimester of pregnancy: a systematic review
Authors: Niloofar Darvishi
Alireza Daneshkhah
Behnam Khaledi-Paveh
Aliakbar Vaisi-Raygani
Masoud Mohammadi
Nader Salari
Fateme Darvishi
Alireza Abdi
Rostam Jalali
Publication date: 01-12-2020
Publisher: BioMed Central
Keyword: Restless Legs Syndrome
Published in: BMC Neurology / Issue 1/2020
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-020-01709-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The prevalence of Restless Legs Syndrome/Willis-ekbom disease (RLS/WED) in the third trimester of pregnancy: a systematic review

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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