Top

Radiation Oncology

Published in:

Open Access 01-12-2008 | Research

Reproducibility and geometric accuracy of the fixster system during hypofractionated stereotactic radiotherapy

Authors: Peter Lindvall, Per Bergström, Per-Olov Löfroth, Roger Henriksson, A Tommy Bergenheim

Published in: Radiation Oncology | Issue 1/2008

Abstract

Background

Hypofractionated radiotherapy has been used for the treatment of AVMs and brain metastases. Hypofractionation necessitates the use of a relocatable stereotactic frame that has to be applied on several occasions. The stereotactic frame needs to have a high degree of reproducibility, and patient positioning is crucial to achieve a high accuracy of the treatment.

Methods

In this study we have, by radiological means, evaluated the reproducibility of the isocenter in consecutive treatment sessions using the Fixster frame. Deviations in the X, Y and Z-axis were measured in 10 patients treated with hypofractionated radiotherapy.

Results

The mean deviation in the X-axis was 0.4 mm (range -2.1 – 2.1, median 0.7 mm) and in the Y-axis -0.3 mm (range -1.4 – 0.7, median -0.2 mm). The mean deviation in the Z-axis was -0.6 (range -1.4 – 1.4, median 0.0 mm).

Conclusion

There is a high degree of reproducibility of the isocenter during successive treatment sessions with HCSRT using the Fixster frame for stereotactic targeting. The high reducibility enables a safe treatment using hypofractionated stereotactic radiotherapy.

Available only for authorised users

Lindvall P, Bergstrom P, Lofroth PO, Hariz MI, Henriksson R, Jonasson P, Bergenheim AT: Hypofractionated conformal stereotactic radiotherapy for arteriovenous malformations. Neurosurgery 2003,53(5):1036-42; discussion 1042-3. 10.1227/01.NEU.0000088566.82699.E6CrossRefPubMed

Chang TC, Shirato H, Aoyama H, Ushikoshi S, Kato N, Kuroda S, Ishikawa T, Houkin K, Iwasaki Y, Miyasaka K: Stereotactic irradiation for intracranial arteriovenous malformation using stereotactic radiosurgery or hypofractionated stereotactic radiotherapy. Int J Radiat Oncol Biol Phys 2004,60(3):861-870.CrossRefPubMed

Manning MA, Cardinale RM, Benedict SH, Kavanagh BD, Zwicker RD, Amir C, Broaddus WC: Hypofractionated stereotactic radiotherapy as an alternative to radiosurgery for the treatment of patients with brain metastases. Int J Radiat Oncol Biol Phys 2000,47(3):603-608. 10.1016/S0360-3016(00)00475-2CrossRefPubMed

Aoyama H, Shirato H, Nishioka T, Kagei K, Onimaru R, Suzuki K, Ushikoshi S, Houkin K, Kuroda S, Abe H, Miyasaka K: Treatment outcome of single or hypofractionated single-isocentric stereotactic irradiation (STI) using a linear accelerator for intracranial arteriovenous malformation. Radiother Oncol 2001,59(3):323-328. 10.1016/S0167-8140(01)00303-6CrossRefPubMed

Aoyama H, Shirato H, Onimaru R, Kagei K, Ikeda J, Ishii N, Sawamura Y, Miyasaka K: Hypofractionated stereotactic radiotherapy alone without whole-brain irradiation for patients with solitary and oligo brain metastasis using noninvasive fixation of the skull. Int J Radiat Oncol Biol Phys 2003,56(3):793-800.CrossRefPubMed

Lindvall P, Bergstrom P, P-O L, Henriksson R, Bergenheim AT: Hypofractionated conformal stereotactic radiotherapy alone or in combination with whole brain radiotherapy in patients with cerebral metastases. Int J Rad Oncol Biol Phys

Hall EJ, Brenner DJ: The radiobiology of radiosurgery: rationale for different treatment regimes for AVMs and malignancies. Int J Radiat Oncol Biol Phys 1993,25(2):381-385.CrossRefPubMed

Bergstrom M, Greitz T, Ribbe T: A method of stereotaxic localization adopted for conventional and digital radiography. Neuroradiology 1986,28(2):100-104. 10.1007/BF00327879CrossRefPubMed

Greitz T, Bergstrom M, Boethius J, Kingsley D, Ribbe T: Head fixation system for integration of radiodiagnostic and therapeutic procedures. Neuroradiology 1980,19(1):1-6.PubMed

10.

Delannes M, Daly N, Bonnet J, Sabatier J, Tremoulet M: [Laitinen's stereo-adapter: application to the fractionated cerebral irradiation under stereotaxic conditions]. Neurochirurgie 1990,36(3):167-74; discussion 174-5.PubMed

11.

Ashamalla H, Addeo D, Ikoro NC, Ross P, Cosma M, Nasr N: Commissioning and clinical results utilizing the Gildenberg-Laitinen Adapter Device for X-ray in fractionated stereotactic radiotherapy. Int J Radiat Oncol Biol Phys 2003,56(2):592-598. 10.1016/S0360-3016(03)00119-6CrossRefPubMed

12.

Choi DR, Kim DY, Ahn YC, Huh SJ, Yeo IJ, Nam DH, Lee JI, Park K, Kim JH: Quantitative analysis of errors in fractionated stereotactic radiotherapy. Med Dosim 2001,26(4):315-318. 10.1016/S0958-3947(01)00082-6CrossRefPubMed

13.

Wu A: Physics and dosimetry of the gamma knife. Neurosurg Clin N Am 1992,3(1):35-50.PubMed

14.

Cernica G, de Boer SF, Diaz A, Fenstermaker RA, Podgorsak MB: Dosimetric accuracy of a staged radiosurgery treatment. Phys Med Biol 2005,50(9):1991-2002. 10.1088/0031-9155/50/9/005CrossRefPubMed

15.

Hariz MI, Eriksson AT: Reproducibility of repeated mountings of a noninvasive CT/MRI stereoadapter. Appl Neurophysiol 1986,49(6):336-347. 10.1159/000100163PubMed

16.

Kumar S, Burke K, Nalder C, Jarrett P, Mubata C, A'Hern R, Humphreys M, Bidmead M, Brada M: Treatment accuracy of fractionated stereotactic radiotherapy. Radiother Oncol 2005,74(1):53-59. 10.1016/j.radonc.2004.06.008CrossRefPubMed

Title: Reproducibility and geometric accuracy of the fixster system during hypofractionated stereotactic radiotherapy
Authors: Peter Lindvall
Per Bergström
Per-Olov Löfroth
Roger Henriksson
A Tommy Bergenheim
Publication date: 01-12-2008
Publisher: BioMed Central
Published in: Radiation Oncology / Issue 1/2008
Electronic ISSN: 1748-717X
DOI: https://doi.org/10.1186/1748-717X-3-16

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Reproducibility and geometric accuracy of the fixster system during hypofractionated stereotactic radiotherapy

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 1/2008

High-dose-rate brachytherapy for soft tissue sarcoma in children: a single institution experience

FDG-PET/CT imaging for staging and radiotherapy treatment planning of head and neck carcinoma

Pre-segmented 2-Step IMRT with subsequent direct machine parameter optimisation – a planning study

Surgery vs. radiotherapy in localized prostate cancer. Which is best?

Investigation of the usability of conebeam CT data sets for dose calculation

Prevention of radiochemotherapy-induced toxicity with amifostine in patients with malignant orbital tumors involving the lacrimal gland: a pilot study