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The article by Ullah et al. [1] published by us followed from the paper of Levine and co-workers [2], wherein these authors had expressed their inability to explain the molecular basis for the relative resistance of normal cells to the cytotoxic action of ascorbic acid. Our results are actually in support of the results of Levine and his group. However, they are an attempt to explain one of the aspects of the results of these authors. Therefore, as mentioned in the letter submitted by Rodemeister et al., the question of not supporting the results of Chen et al. [2] does not arise. Although we realize that we have not used tumor cells in our study, such work has already been done by Levine and his group and many other workers as mentioned in our paper. In the discussion of our paper, we say that based on our results with normal cells and the results of various other groups, it is our ‘belief’ that the preferential cytotoxic action of ascorbic acid against cancer cells is explained by the ability of ascorbic acid to mobilize endogenous copper ions. In support of our idea, we have also given several lines of indirect evidence in literature. …