Published in:
01-05-2016 | Letter to the Editor
Reply to the Letter to the Editor regarding “Did we learn something new on pemphigoid autoimmune blistering diseases?” by Nili Tickotsky, CLOI-D-15-00596
Manuscript number: CLOI-D-15-00596
Authors:
Antonio Barone, Paolo Toti
Published in:
Clinical Oral Investigations
|
Issue 4/2016
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Excerpt
The data mining approach is based on information regarding genes which have been associated with PAIBD (pemphigoid autoimmune blistering disease). The ontological data analysis with bioinformatics advanced tools such as STRING (Search Tool for the Retrieval of Interacting Genes/Proteins) can be a method for preliminary identification of the genes involved with the autoimmune bullous skin diseases: obviously, results of each gene have to be confirmed by proper and targeted biological and biophysical experiment. However, in our opinion, the researchers will devote their full attention to the genes associated with PAIBD for which no apparent interaction with the others has been found. …