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Molecular Pain
Published in: Molecular Pain 1/2014

Open Access 01-12-2014 | Poster presentation

Repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex for treating facial neuropathic pain – preliminary results of a randomized, sham-controlled, cross-over study

Authors: Magdalena Lang, Roi Treister, Max Klein, Anne Louise Oaklander

Published in: Molecular Pain | Special Issue 1/2014

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Excerpt

Repetitive transcranial magnetic stimulation (rTMS) noninvasively triggers action potentials in underlying brain cortex intended for therapeutic benefit. Currently marketed for refractory depression, rTMS is under investigation for treating several neurological conditions including pain. Facial neuropathic pain (NP) appears to respond well to rTMS [1]. The primary motor cortex (M1) is established as the best site to stimulate to relieve pain, but the best target within M1 remains unknown [1, 2]. MRI guidance of rTMS permits repeated precise application to specific targets. The aim of this study was to compare pain relief obtained by applying MRI-guided rTMS to the M1 representation of subjects’ painful face vs. to adjacent M1 cortex innervating their non-painful hand. …
Literature
1.
O'Connell NE, Wand BM, Marston L, Spencer S, DeSouza LH: Non-invasive brain stimulation techniques for chronic pain. Cochrane.Database.Syst.Rev 2014, 4: CD008208.PubMed
2.
Leung A, Donohue M, Xu R, Lee R, Lefaucheur JP, Khedr EM, et al.: rTMS for suppressing neuropathic pain: a meta-analysis. J.Pain 2009, 10: 1205–1216. 10.1016/j.jpain.2009.03.010PubMedCrossRef
3.
Lefaucheur JP, Drouot X, Menard-Lefaucheur I, Zerah F, Bendib B, Cesaro P, et al.: Neurogenic pain relief by repetitive transcranial magnetic cortical stimulation depends on the origin and the site of pain. Journal of Neurology, Neurosurgery & Psychiatry 2004, 75: 612–616. 10.1136/jnnp.2003.022236CrossRef
Metadata
Title
Repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex for treating facial neuropathic pain – preliminary results of a randomized, sham-controlled, cross-over study
Authors
Magdalena Lang
Roi Treister
Max Klein
Anne Louise Oaklander
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Molecular Pain / Issue Special Issue 1/2014
Electronic ISSN: 1744-8069
DOI
https://doi.org/10.1186/1744-8069-10-S1-P6

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