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Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 2/2006

01-02-2006 | Clinical Investigation

Repeatability and reproducibility of optic nerve head topography using the retinal thickness analyzer

Authors: Esther M. Hoffmann, Felipe A. Medeiros, Christina Kramann, Norbert Pfeiffer, Franz H. Grus

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 2/2006

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Abstract

Objective

The objective was to determine the reproducibility and repeatability of topographic disk parameters with the retinal thickness analyzer (RTA).

Methods

Thirty-nine eyes of 39 healthy subjects were included. Three observers performed three consecutive measurements of optic disk topography independently. Combined repeatability (intra-observer component of variability) and reproducibility (inter-observer component of variability, R and R) was assessed by variance component analysis.

Results

Six topographic parameters (disk area, cup area, cup volume, mean cup depth, maximum depth, and cup shape measure) revealed an acceptable repeatability and reproducibility expressed as the percentage of the total measurement variability (range 17.6–28.4%). The average reproducibility and repeatability of all optic disk parameters measured using the RTA was not acceptable (combined R and R = 33.4%).

Conclusions

Repeatability and reproducibility of the optic disk topography analysis using the RTA reveals a high variation, and should, therefore, be interpreted carefully for glaucoma diagnosis and for monitoring the disease.
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Metadata
Title
Repeatability and reproducibility of optic nerve head topography using the retinal thickness analyzer
Authors
Esther M. Hoffmann
Felipe A. Medeiros
Christina Kramann
Norbert Pfeiffer
Franz H. Grus
Publication date
01-02-2006
Publisher
Springer-Verlag
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 2/2006
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-005-0027-2

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