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Urolithiasis
Published in: Urolithiasis 3/2017

01-06-2017 | Original Paper

Renal stones composition in vivo determination: comparison between 100/Sn140 kV dual-energy CT and 120 kV single-energy CT

Authors: Matteo Bonatti, Fabio Lombardo, Giulia A. Zamboni, Patrizia Pernter, Armin Pycha, Roberto Pozzi Mucelli, Giampietro Bonatti

Published in: Urolithiasis | Issue 3/2017

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Abstract

The objective of this study is to compare in vivo, the accuracy of single-energy CT (SECT) and dual-energy CT (DECT) in renal stone characterization. Retrospective study approved by the IRB. 30 patients with symptomatic urolithiasis who underwent CT on a second-generation dual-source scanner with a protocol that included low-dose 120 kV scan followed by 100/Sn140 kV dual-energy scan have been included. Stone composition was classified as uric acid, cystine or calcium oxalates, and phosphates according to attenuation values at 120 kV and to 100/Sn140 kV attenuation ratios and compared with the infrared spectroscopy analysis. 50 stones were detected in 30 patients. SECT correctly assessed stone composition in 52 % of the cases, DECT in 90 %. Sensitivity, specificity, positive predictive value, and negative predictive value in differentiating uric acid vs. non-uric acid stones were 0.94, 0.72, 0.64, and 0.96 for SECT and 1.00, 0.94, 1.00, and 0.96 for DECT, respectively. DECT significantly performs better than SECT in characterising renal stones in vivo, and may represent a useful tool for treatment planning.
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Metadata
Title
Renal stones composition in vivo determination: comparison between 100/Sn140 kV dual-energy CT and 120 kV single-energy CT
Authors
Matteo Bonatti
Fabio Lombardo
Giulia A. Zamboni
Patrizia Pernter
Armin Pycha
Roberto Pozzi Mucelli
Giampietro Bonatti
Publication date
01-06-2017
Publisher
Springer Berlin Heidelberg
Published in
Urolithiasis / Issue 3/2017
Print ISSN: 2194-7228
Electronic ISSN: 2194-7236
DOI
https://doi.org/10.1007/s00240-016-0905-6

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