Published in:
01-12-2016 | Technical Note
Renal Angiomyolipoma: Mid- to Long-Term Results Following Embolization with Onyx
Authors:
Narayanan Thulasidasan, Srividhiya Sriskandakumar, Shahzad Ilyas, Tarun Sabharwal
Published in:
CardioVascular and Interventional Radiology
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Issue 12/2016
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Abstract
Purpose
Percutaneous transcatheter embolization is currently the preferred treatment for ruptured or enlarging renal angiomyolipoma (AML), although the optimum choice of embolic material has not yet been established. We present mid- to long-term outcomes following embolization of AMLs with Onyx.
Materials and Methods
Ten AMLs in seven patients (including two with tuberous sclerosis) were embolized with Onyx. Patients were followed-up clinically, with tumour size and renal function measured pre- and post-procedure.
Results
Mean pre-treatment AML size was 63.4 mm (range 42–100). Mean clinical follow-up was 431.4 days (range 153–986) and imaging follow-up 284.2 days (range 30–741). There was no haemorrhage from treated lesions within the follow-up period. Of patients who had cross-sectional imaging pre- and post-procedure, mean decrease in AML size of 22 mm was seen after Onyx embolization (p = 0.0058, 95 % CI 9.13–34.87). No significant difference between serum creatinine was seen pre- and post-procedure (p = 0.54, 95 % CI 8.63–4.85).
Conclusions
Onyx embolization of renal AMLs is effective in the medium to long term, with theoretical benefits in safety and durability of result.