Published in:
01-02-2004 | Poster presentation
Remifentanil-based analgesia and sedation is well tolerated when administered for up to 10 days in mechanically ventilated ICU patients
Authors:
A Karabinis, M Malbrain, J Bakker, T Jensen, P Germann, D Breen, P Parkinson
Published in:
Critical Care
|
Special Issue 1/2004
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Excerpt
Remifentanil's titratability and rapid organ-independent metabolism make it ideally suited for use in critically ill patients. Establishing safety in this population is important as studies of remifentanil for greater than 3 days are limited. This study compared the safety and efficacy of remifentanil-based analgesia and sedation (RBA) with hypnotic-based sedation (HBS), in 105 ICU patients with medical conditions requiring long-term (up to 10 days) mechanical ventilation. …