Published in:
01-02-2004 | Poster presentation
Remifentanil-based analgesia and sedation facilitates more rapid and predictable time to neurological assessments
Authors:
A Karabinis, K Mandragos, S Stergiopoulos, A Komnos, J Soukup, B Speelberg, A Kirkham
Published in:
Critical Care
|
Special Issue 1/2004
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Excerpt
Predictable pharmacokinetics and organ-independent elimination allows remifentanil hydrochloride (Remi) to be easily titrated to provide optimal analgesia with rapid dissipation of effects even after prolonged infusions in critically ill patients. Remi-based analgesia and sedation supplemented with propofol (P) or midazolam (Mid) was compared with a hypnotic-based technique using fentanyl (Fent) or morphine (Morph) in combination with P or Mid for up to 5 days in 161 mechanically ventilated neurotrauma patients. …