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01-10-2011 | Review

Relationship between serum RANKL and RANKL in bone

Authors: D. M. Findlay, G. J. Atkins

Published in: Osteoporosis International | Issue 10/2011

Abstract

It is now well accepted that the molecule receptor activator of NFκB ligand (RANKL) and osteoprotegerin play key roles in regulating physiological and pathological bone turnover. There are a large number of published reports of circulating RANKL levels in both health and pathology. However, interpretation of these data has been elusive, and the relationship between circulating RANKL and RANKL levels in bone is still not clear. This review explores this subject, documenting the possible origins of circulating RANKL and suggesting additional information that is required before serum RANKL levels can provide useful diagnostic or research information.

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Title: Relationship between serum RANKL and RANKL in bone
Authors: D. M. Findlay
G. J. Atkins
Publication date: 01-10-2011
Publisher: Springer-Verlag
Published in: Osteoporosis International / Issue 10/2011
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-011-1740-9

At a glance: The STEP trials

Springer Medicine

Relationship between serum RANKL and RANKL in bone

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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