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Sport Sciences for Health
Published in: Sport Sciences for Health 2/2018

01-08-2018 | Original Article

Rehabilitation of hamstring strains: does a single injection of platelet-rich plasma improve outcomes? (Clinical study)

Authors: Ahmed Gaballah, Adham Elgeidi, Eadric Bressel, Naglaa Shakrah, Azza Abd-Alghany

Published in: Sport Sciences for Health | Issue 2/2018

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Abstract

Purpose

The study aims to elucidate the effects of single platelet-rich plasma (PRP) injection combined with rehabilitation exercises on growth factor concentrations and muscle strength following hamstring tear injury.

Methods

17 physically active male athletes (22.3 years; 1.80 m; 74.7 kg; 24.9 kg/m2) with a 2nd-grade acute hamstring tear were randomized to a treatment group (n = 8) or control group (n = 9). Both groups received the same physical rehabilitation program for 8 weeks; however, only the treatment group received an autologous single PRP injection. Growth factor concentrations, hamstring strength (HS), knee flexion range of motion (KFROM), and return time to play (RTP) were collected at baseline, and 4 and 8 weeks.

Results

Athletes in the PRP group demonstrated at 4 weeks a significantly higher concentration in IGF-1, FGF-2, VEGF, and PDGF than that the control group demonstrated (p < 0.004). However, neither HS nor KFROM showed any significant differences between groups at 8 weeks (p > 0.05), but HS was significant at 4 weeks (p > 0.002).

Conclusion

PRP injection combined with physical rehabilitation for hamstring tear was more effective in growth factor concentration and return time to play than the physical rehabilitation alone.
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Metadata
Title
Rehabilitation of hamstring strains: does a single injection of platelet-rich plasma improve outcomes? (Clinical study)
Authors
Ahmed Gaballah
Adham Elgeidi
Eadric Bressel
Naglaa Shakrah
Azza Abd-Alghany
Publication date
01-08-2018
Publisher
Springer Milan
Published in
Sport Sciences for Health / Issue 2/2018
Print ISSN: 1824-7490
Electronic ISSN: 1825-1234
DOI
https://doi.org/10.1007/s11332-018-0474-x

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