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Graefe's Archive for Clinical and Experimental Ophthalmology

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10-11-2023 | Refractive Surgery | Cornea

Factors associated with changes in posterior corneal surface following laser-assisted in situ keratomileusis

Authors: Achia Nemet, Dror Ben Ephraim Noyman, Waseem Nasser, Tzahi Sela, Gur Munzer, Shawn Sapir, Michael Mimouni, Igor Kaiserman

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 4/2024

Abstract

Purpose

To identify factors associated with changes in the posterior corneal curvature following laser-assisted in situ keratomileusis (LASIK).

Methods

This retrospective study included myopic astigmatic eyes that underwent LASIK between January and December 2013 at Care-Vision Laser Center, Tel-Aviv, Israel. The average posterior keratometry was measured with the Sirius device at a radius of 3 mm from the center. The correlations between the surgically induced change in average posterior keratometry and preoperative parameters such as preoperative sphere, cylinder, spherical equivalent, central corneal thickness (CCT), refraction, Baiocchi Calossi Versaci (BCV) index, ablation depth, percent of tissue altered (PTA), and residual stromal bed (RSB) are reported.

Results

A total of 115 eyes with a mean age of 32.5 ± 8.3 years (range 22–56 years) were included. Central corneal thickness (p < 0.005), preoperative sphere (p < 0.001), spherical equivalent (p < 0.005), and preoperative posterior inferior/superior ratio (p < 0.05) were all significantly correlated with the percentage of change in the mean posterior K. According to ranked stepwise multiple regression analysis, 22% of the variance of change in posterior K could be explained by the examined factors. The factors that remained significant were the percentage of change in posterior inferior/superior ratio, preoperative subjective sphere, and preoperative mean posterior K (for all, p < 0.001).

Conclusions

The percentage of change in posterior inferior/superior ratio, subjective sphere, and preoperative mean posterior K are all correlated with change in the mean posterior K after LASIK. Understanding of the variables that can influence posterior corneal changes following refractive surgery may play a role in the prevention of iatrogenic keratectasia.

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Title: Factors associated with changes in posterior corneal surface following laser-assisted in situ keratomileusis
Authors: Achia Nemet
Dror Ben Ephraim Noyman
Waseem Nasser
Tzahi Sela
Gur Munzer
Shawn Sapir
Michael Mimouni
Igor Kaiserman
Publication date: 10-11-2023
Publisher: Springer Berlin Heidelberg
Keywords: Refractive Surgery
Keratomileusis
Laser
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 4/2024
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-023-06295-8

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Springer Medicine

Factors associated with changes in posterior corneal surface following laser-assisted in situ keratomileusis

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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