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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-12-2020 | Refractive Errors | Retinal Disorders

Clinical features of simple hemorrhage and myopic choroidal neovascularization associated with lacquer cracks in pathologic myopia

Authors: Peifang Ren, Li Lu, Xuyuan Tang, Hong Lu, Yuan Zhao, Dinghua Lou, Wei Han

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 12/2020

Abstract

Purpose

To investigate the clinical features of simple hemorrhage (SH) and myopic choroidal neovascularization (mCNV) lesions in pathologic myopia (PM) accompanied with lacquer cracks (LCs).

Methods

Altogether 105 PM subjects were recruited with fifty-eight eyes categorized as group LC + SH and sixty eyes as group LC + mCNV. LCs were categorized into stellate and linear subtypes. Eye fundus photography, optical coherence tomography, fluorescein angiography, and indocyanine green angiography were performed. Clinical demographic data, PM maculopathy, peripapillary atrophy, and macular choroidal thickness (mCT) were documented.

Results

Significant differences in age, gender, BCVA, and PM atrophies were observed between LC + SH and LC + mCNV groups. The stellate LC was more common in elder subjects with more severe chorioretinal atrophy and thinner mCT compared with linear LCs (P < 0.05). The mCT in group LC + SH was significantly larger than group LC + CNV (P < 0.001), especially in temporal, inferior, and superior locations of macula. The mCT showed correlation with age (P < 0.001)with a decreasing rate of 0.696 μm/year.

Conclusions

SH tended to initially occur in younger subjects with linear LCs. mCNV was more common in elder subjects with severe chorioretinal atrophy. Stellate LCs were associated with the worse PM lesions.

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Title: Clinical features of simple hemorrhage and myopic choroidal neovascularization associated with lacquer cracks in pathologic myopia
Authors: Peifang Ren
Li Lu
Xuyuan Tang
Hong Lu
Yuan Zhao
Dinghua Lou
Wei Han
Publication date: 01-12-2020
Publisher: Springer Berlin Heidelberg
Keyword: Refractive Errors
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 12/2020
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-020-04778-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical features of simple hemorrhage and myopic choroidal neovascularization associated with lacquer cracks in pathologic myopia

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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