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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2008

01-03-2008 | Letter to the Editor

Reducing Local Recurrence after Breast-Conserving Surgery for Breast Cancer

Authors: Theodore Liakakos, MD, Georgios Baltogiannis, MD

Published in: Annals of Surgical Oncology | Issue 3/2008

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Excerpt

In a recent issue of the journal, Olson et al.1 reported on intraoperative margin assessment during the proposed frozen section analysis. This method reduced the rates of re-excision and local recurrence in patients treated with breast-conserving surgery (BCS). The authors emphasized the need for tumor-free microscopic resection lines. Should the goal of negative margins always be considered or, with the availability of effective adjuvant treatments, is it of little importance with regard to overall survival? …
Literature
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Olson TP, Harter J, Munoz A, Mahvi DM, Breslin T. Frozen section analysis for intraoperative margin assessment during breast-conserving surgery results in low rates of re-excision and local recurrence. Ann Surg Oncol. 2007 Aug 3; [Epub ahead of print]
2.
Bartelink H, Horiot JC, Poortmans PM, et al. Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-year results of the randomized boost versus no boost EORTC 22881-10882 trial. J Clin Oncol 2007;25(22):3259–65PubMedCrossRef
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Roukos DH. Adjuvant chemoradiotherapy in gastric cancer: wave goodbye to extensive surgery? Ann Surg Oncol 2002;9(3):220–1PubMedCrossRef
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Bollet MA, Sigal-Zafrani B, Mazeau V, et al. Age remains the first prognostic factor for loco-regional breast cancer recurrence in young (<40 years) women treated with breast conserving surgery first. Radiother Oncol 2007;82(3):272–80PubMedCrossRef
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Roukos DH, Murray S, Briasoulis E. Molecular genetic tools shape a roadmap towards a more accurate prognostic prediction and personalized management of cancer. Cancer Biol Ther 2007;6(3):308–12PubMedCrossRef
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Agnantis NJ, Paraskevaidis E, Roukos D. Preventing breast, ovarian cancer in BRCA carriers: rational of prophylactic surgery and promises of surveillance. Ann Surg Oncol 2004;11(12):1030–4PubMedCrossRef
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Metadata
Title
Reducing Local Recurrence after Breast-Conserving Surgery for Breast Cancer
Authors
Theodore Liakakos, MD
Georgios Baltogiannis, MD
Publication date
01-03-2008
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 3/2008
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-007-9636-9

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