Published in:
01-03-2010 | Poster presentation
Recurrent early filter clotting in regional citrate anticoagulated continuous venovenous hemodialysis due to undetected antibodies to heparin-platelet factor 4 complexes
Authors:
T Slowinski, I Lieker, M Sander, D Khadzhynov, S Morgera, H Neumayer, H Peters
Published in:
Critical Care
|
Special Issue 1/2010
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Excerpt
We recently published a citrate anticoagulated continuous venovenous hemodialysis (citrate-CVVHD) protocol with variable treatment dose. The protocol was safe and easy to handle and the mean filter lifetime was 61.5 hours [
1]. We here report five cases with unexplained recurrent early filter clotting beside effective citrate anticoagulation due to undetected antibodies to heparin-platelet factor 4 complexes (hep-PF4 ab). …