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01-08-2003 | Neuro

Recurrent delayed brain hemorrhage over years after irradiation and chemotherapy for astrocytoma

Authors: Andreas Hillemanns, Rolf-Dieter Kortmann, Ulrich Herrlinger, Martin Skalej, Hilmar Krapf

Published in: European Radiology | Issue 8/2003

Abstract.

We report on an adult patient with a right frontal astrocytoma, classification WHO II, who suffered from radionecrosis 3.5 years after surgery and combined radio- and chemotherapy. Beginning 8 years after initial diagnosis, repeated episodes of bilateral cerebral hemorrhage and cavitation occurred. This case description emphasizes the possibility of repeated hemorrhage as a delayed reaction to brain irradiation and chemotherapy.

Poussaint TY, Siffert J, Barnes PD, Pomeroy SL, Goumnerova LC, Anthony DC, Sallan SE et al. (1995) Hemorrhagic vasculopathy after treatment of central nervous system neoplasia in childhood: diagnosis and follow-up. Am J Neuroradiol 16:693–699

Tamura M, Ono N, Zama A, Fujimaki H, Ohye C (1993) Delayed brain hemorrhage associated with prophylactic whole brain irradiation for pediatric malignant brain tumor: a case report. Childs Nerv Syst 9:300–301

Allen JC, Miller DC, Budzilovich GN, Epstein FJ (1991) Brain and spinal cord hemorrhage in long-term survivors of malignant pediatric brain tumors: a possible late effect of therapy. Neurology 41:148–150

Valk PE, Dillon WP (1991) Radiation injury of the brain. Am J Neuroradiol 12:45–62

Chung E, Bodensteiner J, Hogg JP (1992) Spontaneous intracerebral hemorrhage: a very late delayed effect of radiation therapy. J Child Neurol 7:259–263

Woo E, Chan YF, Lam K, Lok AS, Yu YL, Huang CY (1987) Apoplectic intracerebral hemorrhage: an unusual complication of cerebral radiation necrosis. Pathology 19:95–98

Cheng KM, Chan CM, Fu YT, Ho LC, Cheung FC, Law CK (2001) Acute hemorrhage in late radiation necrosis of the temporal lobe: report of five cases and review of the literature. J Neurooncol 51:143–150

Kawano H, Sato K, Hosotani K, Kubota T, Goya T, Arikawa S, Wakisaka S (1996) Repeating hemorrhage with a long duration after radiotherapy for glioma: radiological and histological observations. Noshuyo Byori 13:85–92

Sheline GE, Wara WM, Smith V (1980) Therapeutic irradiation and brain injury. Int J Radiat Oncol Biol Phys 6:1215–1228

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Pendlebury WW, Anderson ML, Goldsby RE, Sullivan JK (1991) Intracerebral hemorrhage as a complication of delayed radionecrosis. J Neuropathol Exp Neurol 50:370

Title: Recurrent delayed brain hemorrhage over years after irradiation and chemotherapy for astrocytoma
Authors: Andreas Hillemanns
Rolf-Dieter Kortmann
Ulrich Herrlinger
Martin Skalej
Hilmar Krapf
Publication date: 01-08-2003
Publisher: Springer-Verlag
Published in: European Radiology / Issue 8/2003
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-002-1635-4

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Springer Medicine

Recurrent delayed brain hemorrhage over years after irradiation and chemotherapy for astrocytoma

Abstract.

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract.

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