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Published in: BMC Neurology 1/2012

Open Access 01-12-2012 | Case report

Recurrent aseptic meningitis in association with Kikuchi-Fujimoto disease: case report and literature review

Authors: Tomoko Komagamine, Takahide Nagashima, Masaru Kojima, Norito Kokubun, Toshiki Nakamura, Kenich Hashimoto, Kazuhito Kimoto, Koichi Hirata

Published in: BMC Neurology | Issue 1/2012

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Abstract

Background

Kikuchi Fujimoto disease (KFD), or histiocytic necrotising lymphadenitis, is a benign and self-limiting condition characterised by primarily affecting the cervical lymph nodes. Recurrent aseptic meningitis in association with KFD is extremely rare and remains a diagnostic challenge.

Case presentation

We report a 28-year-old man who presented 7 episodes of aseptic meningitis associated with KFD over the course of 7 years. Histopathological findings of enlarged lymph nodes led to the diagnosis of KFD. The patient’s headache and lymphadenopathy spontaneously resolved without any sequelae.

Conclusions

A diagnosis of KFD should be considered when enlarged cervical lymph nodes are observed in patients with recurrent aseptic meningitis. A long-term prognosis remains uncertain, and careful follow-up is preferred.
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Metadata
Title
Recurrent aseptic meningitis in association with Kikuchi-Fujimoto disease: case report and literature review
Authors
Tomoko Komagamine
Takahide Nagashima
Masaru Kojima
Norito Kokubun
Toshiki Nakamura
Kenich Hashimoto
Kazuhito Kimoto
Koichi Hirata
Publication date
01-12-2012
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2012
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/1471-2377-12-112

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