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04-06-2022 | Rectal Cancer | Original Article

Postoperative pain management after concomitant sacrectomy for locally recurrent rectal cancer

Authors: Masatoshi Kitakaze, Mamoru Uemura, Yuta Kobayashi, Masakatsu Paku, Masaaki Miyo, Yusuke Takahashi, Masakazu Miyake, Takeshi Kato, Masataka Ikeda, Shiki Fujino, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Hirofumi Yamamoto, Tsunekazu Mizushima, Mitsugu Sekimoto, Yuichiro Doki, Hidetoshi Eguchi

Published in: Surgery Today | Issue 11/2022

Abstract

Purpose

To assess pain management in patients post-sacrectomy, focusing on opioid use, and to identify the factors associated with postoperative pain.

Methods

Patients who underwent resection of locally recurrent rectal cancer (LRRC) with concomitant sacrectomy at one of two hospitals between 2007 and 2020 were reviewed retrospectively. We examined the use of opioids preoperatively and postoperatively. Patients were classified into high and low sacrectomy groups based on the sacral bone resection level passing through the S3 vertebra.

Results

Sixty-four patients were enrolled. Opioid use was significantly higher in the high sacrectomy group than in the low sacrectomy group at all times assessed: on postoperative days 7, 14, 30, 90, 180, and 365. Opioid use 3 months after locally recurrent rectal cancer surgery was significantly higher in patients with local re-recurrence of the tumor than in those without re-recurrence (p < 0.05), and the median morphine-equivalent opioid use 3 months postoperatively was significantly higher in the high sacrectomy group (30 vs. 0 mg/day; p < 0.05).

Conclusions

Opioid use after concomitant sacrectomy for LRRC was higher in the high sacrectomy group. Prolonged postoperative pain or increasing pain was associated with local recurrence.

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Title: Postoperative pain management after concomitant sacrectomy for locally recurrent rectal cancer
Authors: Masatoshi Kitakaze
Mamoru Uemura
Yuta Kobayashi
Masakatsu Paku
Masaaki Miyo
Yusuke Takahashi
Masakazu Miyake
Takeshi Kato
Masataka Ikeda
Shiki Fujino
Takayuki Ogino
Norikatsu Miyoshi
Hidekazu Takahashi
Hirofumi Yamamoto
Tsunekazu Mizushima
Mitsugu Sekimoto
Yuichiro Doki
Hidetoshi Eguchi
Publication date: 04-06-2022
Publisher: Springer Nature Singapore
Keywords: Rectal Cancer
Rectal Cancer
Opioids
Opioids
Morphine
Colorectal Cancer
Colorectal Cancer
Published in: Surgery Today / Issue 11/2022
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-022-02522-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Postoperative pain management after concomitant sacrectomy for locally recurrent rectal cancer

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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