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Published in: Annals of Surgical Oncology 13/2020

01-12-2020 | Rectal Cancer | ASO Author Reflections

ASO Author Reflections: Is CRS/HIPEC an Indication to Divert Rectal Anastomosis?

Authors: Ekaterina Baron, MD, Vadim Gushchin, MD, FACS, Mary Caitlin King, BS, Armando Sardi, MD, FACS

Published in: Annals of Surgical Oncology | Issue 13/2020

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Excerpt

Up to 40% of patients with peritoneal carcinomatosis require rectal removal during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) to achieve a complete cytoreduction;1 however, the safest approach of rectal reconstruction in these patients is unclear, as the role of protective ostomy is mostly investigated in classic rectal cancer surgery.2 While the level of rectal anastomosis performed during CRS/HIPEC is usually higher than in rectal cancer surgery since the main goal is to achieve peritoneal clearance rather than a clear rectal margin with total mesorectum excision, CRS/HIPEC itself might be an unfavorable background for anastomosis due to significant surgical trauma, extended operative time, extensive blood loss, fluid overload, and chemical exposure. Therefore, HIPEC surgeons frequently divert even high rectal anastomoses.3
Literature
1.
go back to reference von Breitenbuch P, Piso P, Schlitt HJ. Safety of rectum anastomosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. J Surg Oncol. 2018;118(3):551–6. von Breitenbuch P, Piso P, Schlitt HJ. Safety of rectum anastomosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. J Surg Oncol. 2018;118(3):551–6.
2.
go back to reference Montedori A, Cirocchi R, Farinella E, Sciannameo F, Abraha I. Covering ileo- or colostomy in anterior resection for rectal carcinoma. Cochrane Database Syst Rev. 2010;(5):CD006878. Montedori A, Cirocchi R, Farinella E, Sciannameo F, Abraha I. Covering ileo- or colostomy in anterior resection for rectal carcinoma. Cochrane Database Syst Rev. 2010;(5):CD006878.
3.
go back to reference Pakraftar S, Ramalingam L, Shuai Y, et al. Institutional experience with ostomies created during cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion. Ann Surg Oncol. 2017;24(13):3811–7.CrossRef Pakraftar S, Ramalingam L, Shuai Y, et al. Institutional experience with ostomies created during cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion. Ann Surg Oncol. 2017;24(13):3811–7.CrossRef
Metadata
Title
ASO Author Reflections: Is CRS/HIPEC an Indication to Divert Rectal Anastomosis?
Authors
Ekaterina Baron, MD
Vadim Gushchin, MD, FACS
Mary Caitlin King, BS
Armando Sardi, MD, FACS
Publication date
01-12-2020
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 13/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-020-08494-7

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