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International Journal of Colorectal Disease

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01-03-2021 | Rectal Cancer | Review

A meta-analysis of the role of diverting ileostomy after rectal cancer surgery

Authors: Nasir Zaheer Ahmad, Muhammad Hasan Abbas, Saad Ullah Khan, Amjad Parvaiz

Published in: International Journal of Colorectal Disease | Issue 3/2021

Abstract

Purpose

Anastomotic leak is a feared complication of rectal cancer surgery. A diverting stoma is believed to act as a safety mechanism against this undesirable outcome. This meta-analysis aimed to examine the role of loop ileostomy in the prevention of this complication.

Methods

The Medline, Embase and Cochrane databases were searched for randomized controlled trials (RCTs) comparing anastomotic complications after rectal cancer surgery in the presence or absence of diverting ileostomy. The need for reoperation and postoperative complications were also analysed. The length of hospital stay, intraoperative blood loss and operating time were analysed as secondary endpoints.

Results

A significantly higher number of anastomotic leaks was detected in patients with no diverting ileostomies than in those with diversion (odds ratio (OR) 0.292 and 95% confidence interval (CI) 0.177–0.481), and more patients required reoperations in this group (OR 0.219 and 95% CI 0.114–0.422). The rate of complications other than anastomotic leak was significantly higher in patients with diverting ileostomies than in those without (OR 3.337 and 95% CI of 1.570–7.093). The operating time was longer in the ileostomy group than in the no ileostomy group (P 0.001), but no significant differences in the intraoperative blood loss or postoperative hospital stay length were observed between the two groups(P 0.199 and 0.191 respectively).

Conclusion

A lower leak rate in the presence of diverting ileostomy is supported by relatively weak evidence. While mitigating the consequences of leakage, diverting ileostomies lead to numerous other complications. High-quality RCTs are needed before routine ileostomy diversions can be recommended after rectal cancer surgery.

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Title: A meta-analysis of the role of diverting ileostomy after rectal cancer surgery
Authors: Nasir Zaheer Ahmad
Muhammad Hasan Abbas
Saad Ullah Khan
Amjad Parvaiz
Publication date: 01-03-2021
Publisher: Springer Berlin Heidelberg
Keywords: Rectal Cancer
Rectal Cancer
Enterostomy
Ileostomy
Enterostomy
Published in: International Journal of Colorectal Disease / Issue 3/2021
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-020-03771-z

At a glance: The STEP trials

Springer Medicine

A meta-analysis of the role of diverting ileostomy after rectal cancer surgery

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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