Published in:
01-10-2009 | Special Feature
Recent trends of HER-2 examination and a new strategy of trastuzumab therapy for primary and metastatic breast cancer
Author:
Masafumi Kurosumi
Published in:
Breast Cancer
|
Issue 4/2009
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Excerpt
Recently, therapeutic strategies for patients with breast cancer have made rapid advances since the introduction of molecular-targeting therapy using trastuzumab. At the same time, examination of HER-2 status using the IHC and ISH methods has become an established and accepted procedure for selection of breast cancer patients who will likely respond to trastuzumab. Recently, large-scale clinical studies have confirmed the effectiveness of anti-cancer therapies incorporating trastuzumab for metastatic as well as primary breast cancer. …