Recent advancements in corpus luteum development, function, maintenance and regression: Forum introduction

Excerpt

The corpus luteum is a dynamic tissue whose cellular composition is traced to the remnants of the ovarian follicle, neovascularization and infiltration of immune cells. The corpus luteum undergoes dramatic morphological and functional changes throughout its lifespan. Functionally the corpus luteum is responsible for the provision of progesterone in support of pregnancy. Depending on the species and the physiological state, the corpus luteum lifespan can last from less than a day to almost a year. During this time, whether it is during the development, maintenance, or regression stage the corpus luteum function is mediated by a number of influences including steroids, growth factors, gonadotropins, prostaglandins, cytokines, and peptide hormones. The variable expression of theses factors and their receptors control the fate of the corpus luteum. …