Skip to main content
Top
Published in: BMC Primary Care 1/2009

Open Access 01-12-2009 | Research article

Reasons of general practitioners for not prescribing lipid-lowering medication to patients with diabetes: a qualitative study

Authors: Elisabeth AB, Petra Denig, Ton van Vliet, Janny H Dekker

Published in: BMC Primary Care | Issue 1/2009

Login to get access

Abstract

Background

Lipid-lowering medication remains underused, even in high-risk populations. The objective of this study was to determine factors underlying general practitioners' decisions not to prescribe such drugs to patients with type 2 diabetes.

Methods

A qualitative study with semi-structured interviews using real cases was conducted to explore reasons for not prescribing lipid-lowering medication after a guideline was distributed that recommended the use of statins in most patients with type 2 diabetes. Seven interviews were conducted with general practitioners (GPs) in The Netherlands, and analysed using an analytic inductive approach.

Results

Reasons for not-prescribing could be divided into patient and physician-attributed factors. According to the GPs, some patients do not follow-up on agreed medication and others object to taking lipid-lowering medication, partly for legitimate reasons such as expected or perceived side effects. Furthermore, the GPs themselves perceived reservations for prescribing lipid-lowering medication in patients with short life expectancy, expected compliance problems or near goal lipid levels. GPs sometimes postponed the start of treatment because of other priorities. Finally, barriers were seen in the GPs' practice organisation, and at the primary-secondary care interface.

Conclusion

Some of the barriers mentioned by GPs seem to be valid reasons, showing that guideline non-adherence can be quite rational. On the other hand, treatment quality could improve by addressing issues, such as lack of knowledge or motivation of both the patient and the GP. More structured management in general practice may also lead to better treatment.
Appendix
Available only for authorised users
Literature
1.
go back to reference Collins R, Armitage J, Parish S, Sleigh P, Peto R, Heart Protection Study Collaborative Group: MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003, 361: 2005-2016. 10.1016/S0140-6736(03)12475-0.CrossRefPubMed Collins R, Armitage J, Parish S, Sleigh P, Peto R, Heart Protection Study Collaborative Group: MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003, 361: 2005-2016. 10.1016/S0140-6736(03)12475-0.CrossRefPubMed
2.
go back to reference Greving JP, Denig P, de Zeeuw D, Bilo H, Haaijer-Ruskamp FM: Trends in hyperlipidemia and hypertension management in type 2 diabetes patients from 1998–2004: a longitudinal observational study. Cardiovasc Diabetol. 2007, 6: 25-10.1186/1475-2840-6-25.CrossRefPubMedPubMedCentral Greving JP, Denig P, de Zeeuw D, Bilo H, Haaijer-Ruskamp FM: Trends in hyperlipidemia and hypertension management in type 2 diabetes patients from 1998–2004: a longitudinal observational study. Cardiovasc Diabetol. 2007, 6: 25-10.1186/1475-2840-6-25.CrossRefPubMedPubMedCentral
3.
go back to reference Voorham J, Haaijer-Ruskamp FM, Stolk RP, Wolffenbuttel BHR, Denig P, Groningen Initiative to Analyze Type 2 Diabetes Treatment Group: The influence of elevated cardiometabolic risk factor levels on treatment changes in type 2 diabetes. Diabetes Care. 2008, 31: 501-503. 10.2337/dc07-1043.CrossRefPubMed Voorham J, Haaijer-Ruskamp FM, Stolk RP, Wolffenbuttel BHR, Denig P, Groningen Initiative to Analyze Type 2 Diabetes Treatment Group: The influence of elevated cardiometabolic risk factor levels on treatment changes in type 2 diabetes. Diabetes Care. 2008, 31: 501-503. 10.2337/dc07-1043.CrossRefPubMed
4.
go back to reference Teeling M, Bennett K, Feely J: The influence of guidelines on the use of statins: analysis of prescribing trends 1998–2002. Br J Clin Pharmacol. 2005, 59: 227-232. 10.1111/j.1365-2125.2004.02256.x.CrossRefPubMedPubMedCentral Teeling M, Bennett K, Feely J: The influence of guidelines on the use of statins: analysis of prescribing trends 1998–2002. Br J Clin Pharmacol. 2005, 59: 227-232. 10.1111/j.1365-2125.2004.02256.x.CrossRefPubMedPubMedCentral
5.
go back to reference Grant RW, Cagliero E, Murphy-Sheehy P, Singer DE, Nathan DM, Meigs JB: Comparison of hyperglycemia, hypertension, and hypercholesterolemia management in patients with type 2 diabetes. Am J Med. 2002, 112: 603-609. 10.1016/S0002-9343(02)01103-8.CrossRefPubMed Grant RW, Cagliero E, Murphy-Sheehy P, Singer DE, Nathan DM, Meigs JB: Comparison of hyperglycemia, hypertension, and hypercholesterolemia management in patients with type 2 diabetes. Am J Med. 2002, 112: 603-609. 10.1016/S0002-9343(02)01103-8.CrossRefPubMed
6.
go back to reference Cabana MD, Rand CS, Powe NR, et al: Why don't physicians follow clinical practice guidelines? A framework for improvement. JAMA. 1999, 282: 1458-1465. 10.1001/jama.282.15.1458.CrossRefPubMed Cabana MD, Rand CS, Powe NR, et al: Why don't physicians follow clinical practice guidelines? A framework for improvement. JAMA. 1999, 282: 1458-1465. 10.1001/jama.282.15.1458.CrossRefPubMed
7.
8.
go back to reference Safford MM, Shewchuk R, Qu H, et al: Reasons for not intensifying medications: differentiating "clinical inertia" from appropriate care. J Gen Intern Med. 2007, 22: 1648-1655. 10.1007/s11606-007-0433-8.CrossRefPubMedPubMedCentral Safford MM, Shewchuk R, Qu H, et al: Reasons for not intensifying medications: differentiating "clinical inertia" from appropriate care. J Gen Intern Med. 2007, 22: 1648-1655. 10.1007/s11606-007-0433-8.CrossRefPubMedPubMedCentral
9.
go back to reference Kedward J, Dakin L: A qualitative study of barriers to the use of statins and the implementation of coronary heart disease prevention in primary care. Br J Gen Pract. 2003, 53: 684-689.PubMedPubMedCentral Kedward J, Dakin L: A qualitative study of barriers to the use of statins and the implementation of coronary heart disease prevention in primary care. Br J Gen Pract. 2003, 53: 684-689.PubMedPubMedCentral
10.
go back to reference Hickling J, Rogers S, Nazareth I: Barriers to detecting and treating hypercholesterolaemia in patients with ischaemic heart disease: primary care perceptions. Br J Gen Pract. 2005, 55: 534-538.PubMedPubMedCentral Hickling J, Rogers S, Nazareth I: Barriers to detecting and treating hypercholesterolaemia in patients with ischaemic heart disease: primary care perceptions. Br J Gen Pract. 2005, 55: 534-538.PubMedPubMedCentral
11.
go back to reference Yarzebski J, Bujor CF, Goldberg RJ, Spencer F, Lessard D, Gore JM: A community-wide survey of physician practices and attitudes toward cholesterol management in patients with recent acute myocardial infarction. Arch Intern Med. 2002, 162: 797-804. 10.1001/archinte.162.7.797.CrossRefPubMed Yarzebski J, Bujor CF, Goldberg RJ, Spencer F, Lessard D, Gore JM: A community-wide survey of physician practices and attitudes toward cholesterol management in patients with recent acute myocardial infarction. Arch Intern Med. 2002, 162: 797-804. 10.1001/archinte.162.7.797.CrossRefPubMed
12.
go back to reference Khunti K: Use of multiple methods to determine factors affecting quality of care of patients with diabetes. Fam Pract. 1999, 16: 489-494. 10.1093/fampra/16.5.489.CrossRefPubMed Khunti K: Use of multiple methods to determine factors affecting quality of care of patients with diabetes. Fam Pract. 1999, 16: 489-494. 10.1093/fampra/16.5.489.CrossRefPubMed
13.
go back to reference Durack-Bown I, Giral P, d'Ivernois JF, et al: Patients' and physicians' perceptions and experience of hypercholesterolaemia: a qualitative study. Br J Gen Pract. 2003, 53: 851-857.PubMedPubMedCentral Durack-Bown I, Giral P, d'Ivernois JF, et al: Patients' and physicians' perceptions and experience of hypercholesterolaemia: a qualitative study. Br J Gen Pract. 2003, 53: 851-857.PubMedPubMedCentral
14.
go back to reference Weymiller AJ, Montori VM, Jones LA, et al: Helping patients with type 2 diabetes mellitus make treatment decisions: statin choice randomized trial. Arch Intern Med. 2007, 167: 1076-1082. 10.1001/archinte.167.10.1076.CrossRefPubMed Weymiller AJ, Montori VM, Jones LA, et al: Helping patients with type 2 diabetes mellitus make treatment decisions: statin choice randomized trial. Arch Intern Med. 2007, 167: 1076-1082. 10.1001/archinte.167.10.1076.CrossRefPubMed
15.
go back to reference Britten N, Stevenson FA, Barry CA, Barber N, Bradley CP: Misunderstandings in prescribing decisions in general practice: qualitative study. BMJ. 2000, 320: 484-488. 10.1136/bmj.320.7233.484.CrossRefPubMedPubMedCentral Britten N, Stevenson FA, Barry CA, Barber N, Bradley CP: Misunderstandings in prescribing decisions in general practice: qualitative study. BMJ. 2000, 320: 484-488. 10.1136/bmj.320.7233.484.CrossRefPubMedPubMedCentral
16.
go back to reference Parchman ML, Pugh JA, Romero RL, Bowers KW: Competing demands or clinical inertia: the case of elevated glycosylated hemoglobin. Ann Fam Med. 2007, 5: 196-201. 10.1370/afm.679.CrossRefPubMedPubMedCentral Parchman ML, Pugh JA, Romero RL, Bowers KW: Competing demands or clinical inertia: the case of elevated glycosylated hemoglobin. Ann Fam Med. 2007, 5: 196-201. 10.1370/afm.679.CrossRefPubMedPubMedCentral
17.
go back to reference Harries C, Forrest D, Harvey N, McClelland A, Bowling A: Which doctors are influenced by a patient's age? A multi-method study of angina treatment in general practice, cardiology and gerontology. Qual Saf Health Care. 2007, 16: 23-27. 10.1136/qshc.2006.018036.CrossRefPubMedPubMedCentral Harries C, Forrest D, Harvey N, McClelland A, Bowling A: Which doctors are influenced by a patient's age? A multi-method study of angina treatment in general practice, cardiology and gerontology. Qual Saf Health Care. 2007, 16: 23-27. 10.1136/qshc.2006.018036.CrossRefPubMedPubMedCentral
18.
go back to reference Gotto AM: Statin therapy and the elderly: SAGE advice?. Circulation. 2007, 115: 681-683. 10.1161/CIRCULATIONAHA.106.678300.CrossRefPubMed Gotto AM: Statin therapy and the elderly: SAGE advice?. Circulation. 2007, 115: 681-683. 10.1161/CIRCULATIONAHA.106.678300.CrossRefPubMed
19.
go back to reference Hicks PC, Westfall JM, Van Vorst RF, et al: Action or inaction? Decision making in patients with diabetes and elevated blood pressure in primary care. Diabetes Care. 2006, 29: 2580-2585. 10.2337/dc06-1124.CrossRefPubMed Hicks PC, Westfall JM, Van Vorst RF, et al: Action or inaction? Decision making in patients with diabetes and elevated blood pressure in primary care. Diabetes Care. 2006, 29: 2580-2585. 10.2337/dc06-1124.CrossRefPubMed
20.
go back to reference Parnes BL, Main DS, Dickinson LM, et al: Clinical decisions regarding HbA1c results in primary care: a report from CaReNet and HPRN. Diabetes Care. 2004, 27: 13-16. 10.2337/diacare.27.1.13.CrossRefPubMed Parnes BL, Main DS, Dickinson LM, et al: Clinical decisions regarding HbA1c results in primary care: a report from CaReNet and HPRN. Diabetes Care. 2004, 27: 13-16. 10.2337/diacare.27.1.13.CrossRefPubMed
21.
go back to reference Backlund L, Skånér Y, Montgomery H, Bring J, Strender LE: The role of guidelines and the patient's life-style in GPs' management of hypercholesterolaemia. BMC Fam Pract. 2004, 5: 3-10.1186/1471-2296-5-3.CrossRefPubMedPubMedCentral Backlund L, Skånér Y, Montgomery H, Bring J, Strender LE: The role of guidelines and the patient's life-style in GPs' management of hypercholesterolaemia. BMC Fam Pract. 2004, 5: 3-10.1186/1471-2296-5-3.CrossRefPubMedPubMedCentral
22.
go back to reference Foley KA, Denke MA, Kamal-Bahl S, et al: The impact of physician attitudes and beliefs on treatment decisions: lipid therapy in high-risk patients. Med Care. 2006, 44: 421-428. 10.1097/01.mlr.0000208017.18278.1a.CrossRefPubMed Foley KA, Denke MA, Kamal-Bahl S, et al: The impact of physician attitudes and beliefs on treatment decisions: lipid therapy in high-risk patients. Med Care. 2006, 44: 421-428. 10.1097/01.mlr.0000208017.18278.1a.CrossRefPubMed
23.
go back to reference Renders CM, Valk GD, Griffin SJ, Wagner EH, Eijk Van JT, Assendelft WJ: Interventions to improve the management of diabetes in primary care, outpatient, and community settings: a systematic review. Diabetes Care. 2001, 24: 1821-33. 10.2337/diacare.24.10.1821.CrossRefPubMed Renders CM, Valk GD, Griffin SJ, Wagner EH, Eijk Van JT, Assendelft WJ: Interventions to improve the management of diabetes in primary care, outpatient, and community settings: a systematic review. Diabetes Care. 2001, 24: 1821-33. 10.2337/diacare.24.10.1821.CrossRefPubMed
24.
go back to reference van Bruggen JA, Gorter KJ, Stolk RP, Rutten GE: Shared and delegated systems are not quick remedies for improving diabetes care: a systematic review. Prim Care Diabetes. 2007, 1: 59-68. 10.1016/j.pcd.2007.04.004.CrossRefPubMed van Bruggen JA, Gorter KJ, Stolk RP, Rutten GE: Shared and delegated systems are not quick remedies for improving diabetes care: a systematic review. Prim Care Diabetes. 2007, 1: 59-68. 10.1016/j.pcd.2007.04.004.CrossRefPubMed
25.
go back to reference Kasje WN, Denig P, Stewart RE, de Graeff PA, Haaijer-Ruskamp FM: An educational programme for peer review groups to improve treatment of chronic heart failure and diabetes mellitus type 2 in general practice. J Eval Clin Pract. 2006, 12: 613-621. 10.1111/j.1365-2753.2005.00625.x.CrossRefPubMed Kasje WN, Denig P, Stewart RE, de Graeff PA, Haaijer-Ruskamp FM: An educational programme for peer review groups to improve treatment of chronic heart failure and diabetes mellitus type 2 in general practice. J Eval Clin Pract. 2006, 12: 613-621. 10.1111/j.1365-2753.2005.00625.x.CrossRefPubMed
26.
go back to reference Borgermans LAD, Goderis G, Ouwens M, Wens J, Hayrman J, Grol RPTM: Diversity in diabetes care programmes and views on high quality diabetes care: are we in need of a standardized framework. Int J Integrated Care. 2008, 8: e07-CrossRef Borgermans LAD, Goderis G, Ouwens M, Wens J, Hayrman J, Grol RPTM: Diversity in diabetes care programmes and views on high quality diabetes care: are we in need of a standardized framework. Int J Integrated Care. 2008, 8: e07-CrossRef
27.
go back to reference Bowen GA: Naturalistic inquiry and the saturation concept: a research note. Qualitative Research. 2008, 8: 137-152. 10.1177/1468794107085301.CrossRef Bowen GA: Naturalistic inquiry and the saturation concept: a research note. Qualitative Research. 2008, 8: 137-152. 10.1177/1468794107085301.CrossRef
Metadata
Title
Reasons of general practitioners for not prescribing lipid-lowering medication to patients with diabetes: a qualitative study
Authors
Elisabeth AB
Petra Denig
Ton van Vliet
Janny H Dekker
Publication date
01-12-2009
Publisher
BioMed Central
Published in
BMC Primary Care / Issue 1/2009
Electronic ISSN: 2731-4553
DOI
https://doi.org/10.1186/1471-2296-10-24

Other articles of this Issue 1/2009

BMC Primary Care 1/2009 Go to the issue