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Breast Cancer Research
Published in: Breast Cancer Research 2/2005

01-06-2005 | Poster Presentation

Real-time PCR-based expression profiling of BRCA1-induced genes in primary breast tumors

Authors: B Gur, B Bozkurt, O Konu, S Seckin, IG Yulug

Published in: Breast Cancer Research | Special Issue 2/2005

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Excerpt

BRCA1 possesses a number of features common to transcriptional regulatory proteins, suggesting that it may regulate the expression of one or more downstream genes. It is important to determine which genes are transcriptionally influenced by BRCA1 in vivo to explain its role in tumor suppression and in cancer development. In our previous study, a BRCA1 overexpression system enabled us to define the genes whose expression levels were induced in MCF-7 breast cancer cells by using the PCR-dependent suppression subtractive hybridization technique [1]. …
Literature
1.
Atalay A, Crook T, Ozturk M, Yulug IG: Identification of genes induced by BRCA1 in breast cancer cells. Biochem Biophys Res Commun. 2002, 299: 839-846. 10.1016/S0006-291X(02)02751-1.CrossRefPubMed
2.
Metadata
Title
Real-time PCR-based expression profiling of BRCA1-induced genes in primary breast tumors
Authors
B Gur
B Bozkurt
O Konu
S Seckin
IG Yulug
Publication date
01-06-2005
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 2/2005
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr1149

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