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01-09-2013 | Case Report

Reactive Tonsillar Enlargement Showing Strong ¹⁸F-Fdg Uptake During the Follow-Up of Follicular Lymphoma

Authors: Patricia do Socorro Queiroz Feio, Camilla Borges Ferreira Gomes, Alexandre Simões Nogueira, Luciana Yamamoto Almeida, José Vassallo, Fernando Augusto Soares, Oslei Paes Almeida, Jorge Esquiche León

Published in: Head and Neck Pathology | Issue 3/2013

Abstract

The ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has become a standard procedure for the diagnosis, staging, and restaging in lymphoma patients. However, a relative high rate of false-positive results has been reported. We report a case of a 40-year-old man with a previous history of a nodal follicular lymphoma, stage IVA, treated with R-CHOP, which showed strong ¹⁸F-FDG uptake in the Waldeyer’s tonsillar ring during his follow-up, being considered highly suspicious of relapsed lymphoma. A surgical removal of the palatine tonsils and adenoids was performed, which showed reactive follicular hyperplasia. Furthermore, bone marrow biopsy revealed absence of neoplasia. The patient is still in follow-up with no signs of recurrent lymphoma. This case illustrates that, despite the high sensitivity for the detection of recurrent lymphoma, ¹⁸F-FDG uptake should be interpreted with great caution and confirmatory studies should be performed before any therapy.

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Title: Reactive Tonsillar Enlargement Showing Strong 18F-Fdg Uptake During the Follow-Up of Follicular Lymphoma
Authors: Patricia do Socorro Queiroz Feio
Camilla Borges Ferreira Gomes
Alexandre Simões Nogueira
Luciana Yamamoto Almeida
José Vassallo
Fernando Augusto Soares
Oslei Paes Almeida
Jorge Esquiche León
Publication date: 01-09-2013
Publisher: Springer US
Published in: Head and Neck Pathology / Issue 3/2013
Electronic ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-012-0400-5

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Reactive Tonsillar Enlargement Showing Strong ¹⁸F-Fdg Uptake During the Follow-Up of Follicular Lymphoma

Abstract

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Abstract

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