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European Journal of Trauma and Emergency Surgery
Published in: European Journal of Trauma and Emergency Surgery 3/2012

01-06-2012 | Review Article

Randomized controlled trials affecting polytrauma care

Authors: A. Y. Mejaddam, G. C. Velmahos

Published in: European Journal of Trauma and Emergency Surgery | Issue 3/2012

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Abstract

Trauma remains the leading cause of death in the world in patients under 45 years of age. The evaluation, resuscitation, and appropriate management of polytraumatized patients are paramount to successful outcomes. The advance of evidence-based medicine has had a powerful and positive impact on trauma care, even though the nature of many traumatic injuries lends itself poorly to study in a randomized fashion. During the initial management of bleeding patients, hypotensive resuscitation prior to surgical control has found strong support in the literature, and its use has been adopted by many surgeons. Head injury is the most common cause of traumatic death, and while high-level evidence is limited, adherence to management guidelines is associated with improved outcomes. For abdominal trauma, the concept of damage control surgery, while popular, has never been put to the test in a randomized controlled trial. Numerous randomized trials in the field of critical care have affected the management of severely injured patients, including intensive insulin therapy and low tidal volume ventilation in patients with compromised respiratory function. Finally, a multidisciplinary approach to trauma care in designated trauma centers allows for improved outcomes in polytraumatized patients.
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Metadata
Title
Randomized controlled trials affecting polytrauma care
Authors
A. Y. Mejaddam
G. C. Velmahos
Publication date
01-06-2012
Publisher
Springer-Verlag
Published in
European Journal of Trauma and Emergency Surgery / Issue 3/2012
Print ISSN: 1863-9933
Electronic ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-011-0141-2

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