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Open Access 01-05-2024 | Research

Randomized controlled clinical trial on the efficacy of a novel antimicrobial chewing gum in reducing plaque and gingivitis in adolescent orthodontic patients

Authors: Johanna Weber, Konstantin J. Scholz, Isabelle M. Schenke, Florian Pfab, Fabian Cieplik, Karl-Anton Hiller, Wolfgang Buchalla, Camilla Sahm, Christian Kirschneck, Eva Paddenberg-Schubert

Published in: Clinical Oral Investigations | Issue 5/2024

Abstract

Objectives

Chewing gums containing antiseptics or other antimicrobial substances may be effective in reducing plaque and gingivitis. Therefore, the aim of this randomized placebo-controlled clinical trial was to investigate the efficacy of a novel antimicrobial chewing gum containing essential oils (cinnamon, lemon, peppermint) and extracts on reduction of dental plaque and gingivitis as well as on oral health-related quality of life (OHRQoL) in adolescent orthodontic patients.

Materials

52 patients (11-22 years of age) were randomly assigned to use a test chewing gum (COVIDGUM, Clevergum) or a commercially available control chewing gum over a period of 10 days. Approximal plaque index (API), papillary bleeding index (PBI) and an OHRQoL questionnaire for children (COHIP-G19) were assessed at baseline (BL), after 10 days (10d) and 30 days (30d). In addition, oral health and oral hygiene related questions of the COHIP-G19 questionnaire were evaluated separately in subscales at each timepoint. Data were analyzed using non-parametrical statistical procedures (α = 0.05).

Results

API and PBI decreased significantly over time from BL to 10d and from BL to 30d in both groups, without significant differences between the groups. In both groups, the COHIP-G19 score, oral health subscale and oral hygiene subscale decreased significantly over time. Regarding the oral hygiene subscale, the test group showed significantly better scores at 30d (p = 0.011).

Conclusion

Both chewing gums performed similarly effective in terms of reducing plaque accumulation and gingival inflammation and improving OHRQoL.

Clinical relevance

Chewing gums without antimicrobial ingredients may be sufficient to decrease plaque accumulation and gingival inflammation.

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Title: Randomized controlled clinical trial on the efficacy of a novel antimicrobial chewing gum in reducing plaque and gingivitis in adolescent orthodontic patients
Authors: Johanna Weber
Konstantin J. Scholz
Isabelle M. Schenke
Florian Pfab
Fabian Cieplik
Karl-Anton Hiller
Wolfgang Buchalla
Camilla Sahm
Christian Kirschneck
Eva Paddenberg-Schubert
Publication date: 01-05-2024
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 5/2024
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-024-05669-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Randomized controlled clinical trial on the efficacy of a novel antimicrobial chewing gum in reducing plaque and gingivitis in adolescent orthodontic patients

Abstract

Objectives

Materials

Results

Conclusion

Clinical relevance

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Materials

Results

Conclusion

Clinical relevance

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