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01-04-2009 | Case Report

Radio-induced low-grade glioma: report of two cases and review of the literature

Authors: Alessandro D’Elia, Graziella Angelina Melone, Christian Brogna, Anna Formichella, Antonio Santoro, Maurizio Salvati

Published in: Neurological Sciences | Issue 2/2009

Abstract

With the increasing number of cancer survivors, we can observe a population that will present a higher risk of developing secondary long-term toxicities related to adjuvant chemo and radiotherapy regimens. Among these, children surviving from acute lymphoblastic leukemia (ALL) that were treated with prophylactic cranial irradiation represent a group of patients at a high risk of developing secondary brain tumors. Radiation-induced intracranial tumors have been documented since 1950, and today, more than one-hundred cases have been described. We report our experience with two young patients who were hospitalized for low grade gliomas and had a positive anamnesis for ALL and consequent radiotherapy.

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Title: Radio-induced low-grade glioma: report of two cases and review of the literature
Authors: Alessandro D’Elia
Graziella Angelina Melone
Christian Brogna
Anna Formichella
Antonio Santoro
Maurizio Salvati
Publication date: 01-04-2009
Publisher: Springer Milan
Published in: Neurological Sciences / Issue 2/2009
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-009-0017-y

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Radio-induced low-grade glioma: report of two cases and review of the literature

Abstract

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