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Published in: Journal of Cardiothoracic Surgery 1/2015

Open Access 01-12-2015 | Research article

Radial artery vs saphenous vein graft used as the second conduit for surgical myocardial revascularization: long-term clinical follow-up

Authors: Ivana Petrovic, Dusko Nezic, Miodrag Peric, Predrag Milojevic, Olivera Djokic, Dragana Kosevic, Nebojsa Tasic, Bosko Djukanovic, Petar Otasevic

Published in: Journal of Cardiothoracic Surgery | Issue 1/2015

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Abstract

Background

There is ongoing debate regarding the efficacy of the radial artery (RA) as an aortocoronary conduit, with few solid data regarding long-term clinical results. We sought to determine if the use of the RA as the second arterial conduit, beside left internal thoracic artery (LITA), would improve long-term clinical outcome after CABG as compared to saphenous vein graft (SVG).

Methods

Between March 2001 and November 2003, 200 patients underwent isolated CABG and were randomized in 1:1 fashion to receive either LITA and RA grafts or LITA and SVGs. The primary end point was composite of cardiovascular mortality, non-fatal myocardial infarction and need for repeat myocardial revascularization (either surgical or percutaneous).

Results

There was no significant difference in absolute survival, with 12 deaths in each group during the study period (log rank = 0.01, p = 0.979). There were 3 and 2 cardiac deaths in RA and SVG groups, respectively. There was no difference in long-term clinical outcome between the groups (log rank = 0.450, p = 0.509). Eleven patients in RA group had one or more non-fatal events; 7 patients suffered a myocardial infarction, 9 patients underwent percutaneous coronary angioplasty, and 1 patient required redo coronary surgery. Likewise, 13 patients in SVG group had non-fatal event; 7 patients had myocardial infarction, 13 patients had percutaneous coronary intervention and 3 patients required redo coronary surgery. Angiograms were performed in 23 patients in RA group (patency rate 92 %) and 24 in SVG group (patency rate 86 %) (p = 0.67).

Conclusion

In this small randomised study our data indicate that there is no difference in the 8 year clinical outcomes in relatively young patients between those having a RA or a saphenous vein graft used as a second conduit, beside LITA, for surgical myocardial revascularisation.
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Metadata
Title
Radial artery vs saphenous vein graft used as the second conduit for surgical myocardial revascularization: long-term clinical follow-up
Authors
Ivana Petrovic
Dusko Nezic
Miodrag Peric
Predrag Milojevic
Olivera Djokic
Dragana Kosevic
Nebojsa Tasic
Bosko Djukanovic
Petar Otasevic
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2015
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-015-0331-9

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